Cepharanthine

This product is for research use only, not for human use. We do not sell to patients.

Cepharanthine
For small sizes, please check our retail website as below: www.invivochem.com
Size Price Stock
500mg$150Check With Us
1g$250Check With Us
5g$630Check With Us

Cat #: V17927 CAS #: 481-49-2 Purity ≥ 99%

Description: Cepharanthine is a naturally occurring biscoclaurine alkaloid with antiinflammatory and antiviral (against COVID-19) activity.

References: Hijikata A, et al. Evaluating cepharanthine analogues as natural drugs against SARS-CoV-2. FEBS Open Bio. 2022;12(1):285-294

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Molecular Weight (MW)606.71
Molecular FormulaC37H38N2O6
CAS No.481-49-2
SMILES CodeCOC1=CC2=C3C=C1OC4=C(OCO5)C5=CC6=C4[C@@](CC7=CC=C(OC(C(OC)=C8)=CC=C8C[C@@]3([H])N(C)CC2)C=C7)([H])N(C)CC6
Synonyms 6',12'-Dimethoxy-2,2'-dimethyl-6,7-[methylenebis- (oxy)]oxyacanthan; Cepharanthin; O-Methylcepharanoline; Cepharanthine
Preparing Stock Solutions
Solvent volume to be added Mass (the weight of a compound)
Mother liquor concentration 1mg5mg10mg20mg
1mM1.6482 mL8.2412 mL16.4823 mL32.9647 mL
5mM0.3296 mL1.6482 mL3.2965 mL6.5929 mL
10mM0.1648 mL0.8241 mL1.6482 mL3.2965 mL
20mM0.0824 mL0.4121 mL0.8241 mL1.6482 mL
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
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Volume
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Molecular Weight*
The dilution calculator equation
Concentration(start) × Volume(start) = Concentration(final) × Volume(final)

This equation is commonly abbreviated as: C1 V1 = C2 V2

Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals
Step Two: Enter the in vivo formulation
%DMSO + % + %Tween 80 + %ddH2O

Calculation Results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH2O,mix and clarify.
Note:
  • (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
  • (2) Be sure to add the solvent(s) in order.