RO-0335

This product is for research use only, not for human use. We do not sell to patients.

RO-0335
For small sizes, please check our retail website as below: www.invivochem.com
Size Price Stock
100mg$1000Check With Us
250mg$1500Check With Us
500mg$2250Check With Us

Cat #: V13914 CAS #: 867365-76-2 Purity ≥ 99%

Description: RO-0335 is a novel and potent diphenylether nonnucleoside reverse transcriptase inhibitor.

References: Javanbakht H, et al. In vitro resistance development for RO-0335, a novel diphenylether nonnucleoside reverse transcriptase inhibitor. Antiviral Res. 2010;86(2):212-219.

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Molecular Weight (MW)573.22
Molecular FormulaC21H13BrCl2FN3O4S
CAS No.867365-76-2
Preparing Stock Solutions
Solvent volume to be added Mass (the weight of a compound)
Mother liquor concentration 1mg5mg10mg20mg
1mM1.7445 mL8.7227 mL17.4453 mL34.8906 mL
5mM0.3489 mL1.7445 mL3.4891 mL6.9781 mL
10mM0.1745 mL0.8723 mL1.7445 mL3.4891 mL
20mM0.0872 mL0.4361 mL0.8723 mL1.7445 mL
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start) × Volume(start) = Concentration(final) × Volume(final)

This equation is commonly abbreviated as: C1 V1 = C2 V2

Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals
Step Two: Enter the in vivo formulation
%DMSO + % + %Tween 80 + %ddH2O

Calculation Results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH2O,mix and clarify.
Note:
  • (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
  • (2) Be sure to add the solvent(s) in order.