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Cyclouridine (2,2′-Anhydrouridine)

This product is for research use only, not for human use. We do not sell to patients.

Cyclouridine (2,2′-Anhydrouridine)
For small sizes, please check our retail website as below: www.invivochem.com
Size Price Stock
10g$400Check With Us
25g$700Check With Us
50g$1050Check With Us

Cat #: V30705 CAS #: 3736-77-4 Purity ≥ 99%

Description: 2,2'-Anhydrouridine (Cyclouridine; NSC-157148) is a potent inhibitor of uridine phosphorylase (apparent Ki = 2.268 µM) with anticancer and antiviral effects.

References: Drabikowska AK, et al. Inhibitor properties of some 5-substituted uracil acyclonucleosides, and 2,2'-anhydrouridines versus uridine phosphorylase from E. coli and mammalian sources. Biochem Pharmacol. 1987 Dec 1;36(23):4125-8.

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Molecular Weight (MW)226.19
Molecular FormulaC9H10N2O5
CAS No.3736-77-4
SMILES CodeO[C@H]1[C@]2([C@]([H])(N3C(O2)=NC(C=C3)=O)O[C@@H]1CO)[H]
SynonymsNSC 157148; NSC157148; NSC-1571; Cyclouridine; 2,2′-Anhydrouridine;
Preparing Stock Solutions
Solvent volume to be added Mass (the weight of a compound)
Mother liquor concentration 1mg5mg10mg20mg
1mM4.4211 mL22.1053 mL44.2106 mL88.4212 mL
5mM0.8842 mL4.4211 mL8.8421 mL17.6842 mL
10mM0.4421 mL2.2105 mL4.4211 mL8.8421 mL
20mM0.2211 mL1.1053 mL2.2105 mL4.4211 mL
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
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Volume
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Molecular Weight*
The dilution calculator equation
Concentration(start) × Volume(start) = Concentration(final) × Volume(final)

This equation is commonly abbreviated as: C1 V1 = C2 V2

Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals
Step Two: Enter the in vivo formulation
%DMSO + % + %Tween 80 + %ddH2O

Calculation Results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH2O,mix and clarify.
Note:
  • (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
  • (2) Be sure to add the solvent(s) in order.