Tyrothricin

This product is for research use only, not for human use. We do not sell to patients.

For small sizes, please check our retail website as below: www.invivochem.com

Size	Price	Stock
100mg	$1125	To Be Confirmed
200mg	$1685	To Be Confirmed
500mg	$2845	To Be Confirmed

: [email protected] [email protected]

Cat #: V16964 CAS #: 1404-88-2 Purity ≥ 99%

Description: Tyrothricin is a novel and potent antimicrobial polypeptide extracted from Bacillus brevis, consisting of gramicidins and tyrocidins commands broad antimicrobial activity against gram-positive bacteria and some yeasts in vitro.

References: Lang C, et al. Tyrothricin--An underrated agent for the treatment of bacterial skin infections and superficial wounds? Pharmazie. 2016 Jun;71(6):299-305.

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Molecular Weight (MW)	1228.45
Molecular Formula	C65H85N11O13
CAS No.	1404-88-2
SMILES Code	O=C(O)CC[C@@H](C(N[C@H]1CC(N)=O)=O)N[C@@H](CC2=CC=C(O)C=C2)C(N[C@@H](C(C)C)C(N[C@@H](CCCN)C(N[C@@H](CC(C)C)C(N[C@H](CC3=CC=CC=C3)C(N4[C@](CCC4)([H])C(N[C@@H](CC5=CC=CC=C5)C(N[C@H](CC6=CC=CC=C6)C1=O)=O)=O)=O)=O)=O)=O)=O
Synonyms	Hydrotricine; Martricin; Tyrex; Solutricine; Tyrothricin; Bactratycin; Coltirot; Dermotricine; Ginotricina;

Preparing Stock Solutions

Solvent volume to be added	Mass (the weight of a compound)
Mother liquor concentration	1mg	5mg	10mg	20mg
1mM	0.8140 mL	4.0702 mL	8.1403 mL	16.2807 mL
5mM	0.1628 mL	0.8140 mL	1.6281 mL	3.2561 mL
10mM	0.0814 mL	0.4070 mL	0.8140 mL	1.6281 mL
20mM	0.0407 mL	0.2035 mL	0.4070 mL	0.8140 mL

The molarity calculator equation

Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)

Mass

Concentration

Volume

Molecular Weight*

The dilution calculator equation

Concentration_(start) × Volume_(start) = Concentration_(final) × Volume_(final)

This equation is commonly abbreviated as: C₁ V₁ = C₂ V₂

Concentration_(start)

Volume_(start)

Concentration_(final)

Volume_(final)

Step One: Enter information below

Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals

Step Two: Enter the in vivo formulation

%DMSO + % + %Tween 80 + %ddH₂O

Calculation Results:

Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.

Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH₂O,mix and clarify.

Note:

(1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
(2) Be sure to add the solvent(s) in order.