Flucloxacillin

This product is for research use only, not for human use. We do not sell to patients.

Flucloxacillin
For small sizes, please check our retail website as below: www.invivochem.com
Size Price Stock
2g$550To Be Confirmed
5g$1050To Be Confirmed
10g$1575To Be Confirmed

Cat #: V44675 CAS #: 5250-39-5 Purity ≥ 99%

Description: Flucloxacillin (Floxacillin, Floxapen) is a potent and narrow-spectrum beta-lactam antibiotic with activity against gram-positive and gram-negative bacteria.

References: Greimel F, et, al. Efficacy of antibiotic treatment of implant-associated Staphylococcus aureus infections with moxifloxacin, flucloxacillin, rifampin, and combination therapy: an animal study. Drug Des Devel Ther. 2017 Jun 14;11:1729-1736.

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Molecular Weight (MW)453.87
Molecular FormulaC19H17ClFN3O5S
CAS No.5250-39-5
SMILES CodeCc1onc(c1C(=O)N[C@H]2[C@H]3SC(C)(C)[C@@H](N3C2=O)C(=O)O)c4c(F)cccc4Cl
SynonymsFloxacillin; Floxapen; Flucloxacillin; BRL 2039;
ProtocolIn VivoFlucloxacillin (200 mg/kg; i.p.; three times/day, for 21 days; male Wistar rats) has effective against the most common bacterial strains in periprosthetic infection.
Animal modelMale Wistar rats
These protocols are for reference only. InvivoChem does not independently validate these methods.
Preparing Stock Solutions
Solvent volume to be added Mass (the weight of a compound)
Mother liquor concentration 1mg5mg10mg20mg
1mM2.2033 mL11.0164 mL22.0327 mL44.0655 mL
5mM0.4407 mL2.2033 mL4.4065 mL8.8131 mL
10mM0.2203 mL1.1016 mL2.2033 mL4.4065 mL
20mM0.1102 mL0.5508 mL1.1016 mL2.2033 mL
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
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Volume
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Molecular Weight*
The dilution calculator equation
Concentration(start) × Volume(start) = Concentration(final) × Volume(final)

This equation is commonly abbreviated as: C1 V1 = C2 V2

Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals
Step Two: Enter the in vivo formulation
%DMSO + % + %Tween 80 + %ddH2O

Calculation Results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH2O,mix and clarify.
Note:
  • (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
  • (2) Be sure to add the solvent(s) in order.