Stylopine | CAS 7461-02-1 or 4312-32-7

Stylopine

This product is for research use only, not for human use. We do not sell to patients.

For small sizes, please check our retail website as below: www.invivochem.com

Size	Price	Stock
250mg	$950	Check With Us
500mg	$1520	Check With Us
1g	$2280	Check With Us

: [email protected] [email protected]

Cat #: V15370 CAS #: 7461-02-1 or 4312-32-7 Purity ≥ 99%

Description: Stylopine [(±)-Stylopine; Tetrahydrocoptisine; (R,S±)-Stylopine; NSC-110382; NSC-404529] is a naturally occurring isoquinoline alkaloid isolated from C. impatiens with anti-inflammatory and antioxidant activities.

References: Li W, et al. Anti-inflammatory effect of tetrahydrocoptisine from Corydalis impatiens is a function of possible inhibition of TNF-α, IL-6 and NO production in lipopolysaccharide-stimulated peritoneal macrophages through inhibiting NF-κB activation and MAPK pathway. Eur J Pharmacol. 2013 Sep 5;715(1-3):62-71.

Top Publications Citing Invivochem Products

Product Catalog 2022

Guide to Product Handling

Publications Citing InvivoChem Products

Product Promise

Physicochemical and Storage Information
Protocol
Related Biological Data
Stock Solution Preparation
Quality Control Documentation

Molecular Weight (MW)	323.34
Molecular Formula	C19H17NO4
CAS No.	7461-02-1 or 4312-32-7
Storage	-20℃ for 3 years in powder form and for 6 month in solventr
Storage	-80℃ for 5 years in powder form and 2 years in solvent
SMILES Code	C12=CC(OCO3)=C3C=C1C(CC(C=CC4=C5OCO4)=C5C6)N6CC2
Synonyms	NSC 110382; NSC-110382; NSC110382; NSC 404529; NSC-404529; NSC404529; Stylopine; Tetrahydrocoptisine; (R,S±)-Stylopine; (R,S±) Stylopine;

Preparing Stock Solutions

Solvent volume to be added	Mass (the weight of a compound)
Mother liquor concentration	1mg	5mg	10mg	20mg
1mM	3.0927 mL	15.4636 mL	30.9272 mL	61.8544 mL
5mM	0.6185 mL	3.0927 mL	6.1854 mL	12.3709 mL
10mM	0.3093 mL	1.5464 mL	3.0927 mL	6.1854 mL
20mM	0.1546 mL	0.7732 mL	1.5464 mL	3.0927 mL

The molarity calculator equation

Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)

Mass

Concentration

Volume

Molecular Weight*

The dilution calculator equation

Concentration_(start) × Volume_(start) = Concentration_(final) × Volume_(final)

This equation is commonly abbreviated as: C₁ V₁ = C₂ V₂

Concentration_(start)

Volume_(start)

Concentration_(final)

Volume_(final)

Step One: Enter information below

Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals

Step Two: Enter the in vivo formulation

%DMSO + % + %Tween 80 + %ddH₂O

Calculation Results:

Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.

Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH₂O,mix and clarify.

Note:

(1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
(2) Be sure to add the solvent(s) in order.