IVERMECTIN
This product is for research use only, not for human use. We do not sell to patients.
For small sizes, please check our retail website as below: www.invivochem.com
| Size | Price | Stock |
|---|---|---|
| 5g | $200 | Check With Us |
| 10g | $350 | Check With Us |
| 20g | $525 | Check With Us |
: Cat #: V4365 CAS #: 70288-86-7 Purity ≥ 98%
Description: Ivermectin (formerly known as MK-933; Noromectin; Mectizan; Ivomec; L-64047; Pandex) is an effective and widely used antiparasitic medication approved for use in human and veterinary medicine against many types of parasites.
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- Physicochemical and Storage Information
- Protocol
- Related Biological Data
- Stock Solution Preparation
- Quality Control Documentation
| Molecular Weight (MW) | 875.09 |
|---|---|
| Molecular Formula | C₄₈H₇₄O₁₄ |
| CAS No. | 70288-86-7 |
| Storage | -20℃ for 3 years in powder formr |
| -80℃ for 2 years in solvent | |
| SMILES Code | CCC([C@@H]1[C@@H](C)CC[C@]2(CC3C[C@@H](C/C=C(C)/[C@@H](O[C@H]4C[C@H](OC)[C@@H](OC5C[C@H](OC)[C@@H](O)[C@H](C)O5)[C@H](C)O4)[C@@H](C)/C=C/C=C6CO[C@H]7[C@]\6(O)[C@H](C(O3)=O)C=C(C)[C@H]7O)O2)O1)C.C[C@H]8CC[C@@]9(O[C@@H]8C(C)C)CC%10C[C@@H](C/C=C(C)/[C@@H](O[C@H]%11C[C@H](OC)[C@@H](OC%12C[C@H](OC)[C@@H](O)[C@H](C)O%12)[C@H](C)O%11)[C@@H](C)/C=C/C=C%13CO[C@H]%14[C@]\%13(O)[C@H](C(O%10)=O)C=C(C)[C@H]%14O)O9 |
| Synonyms | MK-933; Ivermectin; Ivomec; L 64047;1 Mectizan; MK 933; MK-0933; Noromectin; Pandex. |
| Protocol | In Vitro | In the submicromolar range (EC50=250 nM) the action of Ivermectin (MK-933) is rapid and reversible, resulting in increased amplitude and slowed deactivation of P2X4 channel currents evoked by ATP. Ivermectin (MK-933) markedly increases the potency of ATP and that of the normally low-potency agonist a,b-methylene-ATP in a use- and voltage-independent manner without changing the ion selectivity of P2X4 channels. |
|---|
These protocols are for reference only. InvivoChem does not
independently validate these methods.
| Solvent volume to be added | Mass (the weight of a compound) | |||
|---|---|---|---|---|
| Mother liquor concentration | 1mg | 5mg | 10mg | 20mg |
| 1mM | 1.1427 mL | 5.7137 mL | 11.4274 mL | 22.8548 mL |
| 5mM | 0.2285 mL | 1.1427 mL | 2.2855 mL | 4.5710 mL |
| 10mM | 0.1143 mL | 0.5714 mL | 1.1427 mL | 2.2855 mL |
| 20mM | 0.0571 mL | 0.2857 mL | 0.5714 mL | 1.1427 mL |
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start)
×
Volume(start)
=
Concentration(final)
×
Volume(final)
This equation is commonly abbreviated as: C1 V1 = C2 V2
Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg
Average weight of animals g
Dosing volume per animal µL
Number of animals
Step Two: Enter the in vivo formulation
%DMSO
+
%
+
%Tween 80
+
%ddH2O
Calculation Results:
Working concentration:
mg/ml;
Method for preparing DMSO master liquid:
mg
drug pre-dissolved in
µL
DMSO(Master liquid concentration
mg/mL)
,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation:
Take
µL
DMSO master liquid, next add
µL
PEG300, mix and clarify, next add
µL
Tween 80,mix and clarify, next add
µL
ddH2O,mix and clarify.
Note:
- (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
- (2) Be sure to add the solvent(s) in order.