DHQZ-36
This product is for research use only, not for human use. We do not sell to patients.
For small sizes, please check our retail website as below: www.invivochem.com
| Size | Price | Stock |
|---|---|---|
| 100mg | $530 | In Stock |
| 200mg | $795 | In Stock |
| 500mg | $1340 | In Stock |
: Cat #: V19728 CAS #: 1542098-94-1 Purity ≥ 98%
Description: DHQZ-36 is a novel and potent small molecule retrograde trafficking inhibitor which is able to block infection by several human and monkey polyomaviruses.
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| Molecular Weight (MW) | 384.44 |
|---|---|
| Molecular Formula | C21H18F2N2OS |
| CAS No. | 1542098-94-1 |
| SMILES Code | O=C1N(CC2=CC=C(F)C=C2)C(C3=CC=C(CC)S3)NC4=C1C=C(F)C=C4 |
| Synonyms | DHQZ36; DHQZ-36; DHQZ 36 |
| Protocol | In Vitro | With increasing concentrations of DHQZ 36 there is a significant diminution in the size of parasitophorous vacuoles (LPVs), vacuole sizes are reduced by 30% at 50 μM. These parasites also cause a reduction in the number of parasites per macrophage. Significant parasite loss is observed with as low as 5 μM after treatment with DHQZ 36. Parasites are unable to recover growth when treated with DHQZ 36 at concentrations at or above 12.5 μM. |
|---|
These protocols are for reference only. InvivoChem does not
independently validate these methods.
| Solvent volume to be added | Mass (the weight of a compound) | |||
|---|---|---|---|---|
| Mother liquor concentration | 1mg | 5mg | 10mg | 20mg |
| 1mM | 2.6012 mL | 13.0059 mL | 26.0119 mL | 52.0237 mL |
| 5mM | 0.5202 mL | 2.6012 mL | 5.2024 mL | 10.4047 mL |
| 10mM | 0.2601 mL | 1.3006 mL | 2.6012 mL | 5.2024 mL |
| 20mM | 0.1301 mL | 0.6503 mL | 1.3006 mL | 2.6012 mL |
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
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Concentration
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Volume
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Molecular Weight*
The dilution calculator equation
Concentration(start)
×
Volume(start)
=
Concentration(final)
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Volume(final)
This equation is commonly abbreviated as: C1 V1 = C2 V2
Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg
Average weight of animals g
Dosing volume per animal µL
Number of animals
Step Two: Enter the in vivo formulation
%DMSO
+
%
+
%Tween 80
+
%ddH2O
Calculation Results:
Working concentration:
mg/ml;
Method for preparing DMSO master liquid:
mg
drug pre-dissolved in
µL
DMSO(Master liquid concentration
mg/mL)
,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation:
Take
µL
DMSO master liquid, next add
µL
PEG300, mix and clarify, next add
µL
Tween 80,mix and clarify, next add
µL
ddH2O,mix and clarify.
Note:
- (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
- (2) Be sure to add the solvent(s) in order.