T.cruzi Inhibitor (INVIVO1088 HCI)
This product is for research use only, not for human use. We do not sell to patients.
For small sizes, please check our retail website as below: www.invivochem.com
| Size | Price | Stock |
|---|---|---|
| 250mg | $600 | Check With Us |
| 500mg | $900 | Check With Us |
| 1g | $1350 | Check With Us |
: Cat #: V25152 CAS #: 1350920-22-7 Purity ≥ 99%
Description: N-benzyl-N-Methyl-1-(4-(trifluoroMethyl)benzyl)piperidine-3-carboxaMide is a novel and potent Trypanosoma cruzi inhibitor.
Top Publications Citing Invivochem Products
Publications Citing InvivoChem Products
Product Promise
- Physicochemical and Storage Information
- Protocol
- Related Biological Data
- Stock Solution Preparation
- Quality Control Documentation
| Molecular Weight (MW) | 390.44 |
|---|---|
| Molecular Formula | C22H25F3N2O |
| CAS No. | 1350920-22-7 |
| SMILES Code | O=C(C1CN(CC2=CC=C(C(F)(F)F)C=C2)CCC1)N(CC3=CC=CC=C3)C.[H]Cl |
| Synonyms | T.cruzi-IN-1; T.cruzi Inhibitor; MDK-1088; MDK1088; MDK 1088; MDK-1088 HCl; MDK-1088 hydrochloride |
| Protocol | In Vitro | T.cruzi-IN-1 inhibits Trypanosoma cruzi replication and has an IC50 of 61.6 μM for toxicity. |
|---|
These protocols are for reference only. InvivoChem does not
independently validate these methods.
| Solvent volume to be added | Mass (the weight of a compound) | |||
|---|---|---|---|---|
| Mother liquor concentration | 1mg | 5mg | 10mg | 20mg |
| 1mM | 2.5612 mL | 12.8061 mL | 25.6121 mL | 51.2243 mL |
| 5mM | 0.5122 mL | 2.5612 mL | 5.1224 mL | 10.2449 mL |
| 10mM | 0.2561 mL | 1.2806 mL | 2.5612 mL | 5.1224 mL |
| 20mM | 0.1281 mL | 0.6403 mL | 1.2806 mL | 2.5612 mL |
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start)
×
Volume(start)
=
Concentration(final)
×
Volume(final)
This equation is commonly abbreviated as: C1 V1 = C2 V2
Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg
Average weight of animals g
Dosing volume per animal µL
Number of animals
Step Two: Enter the in vivo formulation
%DMSO
+
%
+
%Tween 80
+
%ddH2O
Calculation Results:
Working concentration:
mg/ml;
Method for preparing DMSO master liquid:
mg
drug pre-dissolved in
µL
DMSO(Master liquid concentration
mg/mL)
,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation:
Take
µL
DMSO master liquid, next add
µL
PEG300, mix and clarify, next add
µL
Tween 80,mix and clarify, next add
µL
ddH2O,mix and clarify.
Note:
- (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
- (2) Be sure to add the solvent(s) in order.