Ponazuril

This product is for research use only, not for human use. We do not sell to patients.

Ponazuril
For small sizes, please check our retail website as below: www.invivochem.com
Size Price Stock
250mg$200Check With Us
500mg$320Check With Us
1g$480Check With Us

Cat #: V6596 CAS #: 69004-04-2 Purity ≥ 99%

Description: Ponazuril is a novel and potent equine protozoal myeloencephalitis (EPM) drug in horses.

References: Sheila M Mitchell, et al. The effects of ponazuril on development of apicomplexans in vitro. J Eukaryot Microbiol. May-Jun 2005;52(3):231-5.

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Product Promise

Promise
Molecular Weight (MW)457.38
Molecular FormulaC18H14F3N3O6S
CAS No.69004-04-2
SMILES CodeO=C1N(C2=CC=C(OC3=CC=C(S(=O)(C(F)(F)F)=O)C=C3)C(C)=C2)C(NC(N1C)=O)=O
SynonymsPonazuril; Toltrazuril sulfone; Marquis; BAY-Vi 9143; BAY-Vi-9143; BAY-Vi9143;
Preparing Stock Solutions
Solvent volume to be added Mass (the weight of a compound)
Mother liquor concentration 1mg5mg10mg20mg
1mM2.1864 mL10.9318 mL21.8637 mL43.7273 mL
5mM0.4373 mL2.1864 mL4.3727 mL8.7455 mL
10mM0.2186 mL1.0932 mL2.1864 mL4.3727 mL
20mM0.1093 mL0.5466 mL1.0932 mL2.1864 mL
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start) × Volume(start) = Concentration(final) × Volume(final)

This equation is commonly abbreviated as: C1 V1 = C2 V2

Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals
Step Two: Enter the in vivo formulation
%DMSO + % + %Tween 80 + %ddH2O

Calculation Results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH2O,mix and clarify.
Note:
  • (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
  • (2) Be sure to add the solvent(s) in order.