NSC-5844 (RE-640)
This product is for research use only, not for human use. We do not sell to patients.
For small sizes, please check our retail website as below: www.invivochem.com
| Size | Price | Stock |
|---|---|---|
| 500mg | $950 | Check With Us |
| 1g | $1490 | Check With Us |
| 5g | $5025 | Check With Us |
: Cat #: V5036 CAS #: 140926-75-6 Purity ≥ 98%
Description: NSC5844 (also known as RE640), a 4-aminoquinoline derivative and a bisquinoline compound, is a novel and potent agonist of C-C chemokine receptor type 1 (CCR1).
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| Molecular Weight (MW) | 383.27 |
|---|---|
| Molecular Formula | C20H16Cl2N4 |
| CAS No. | 140926-75-6 |
| Storage | -20℃ for 3 years in powder formr |
| -80℃ for 2 years in solvent | |
| SMILES Code | ClC1=CC=C2C(NCCNC3=CC=NC4=CC(Cl)=CC=C34)=CC=NC2=C1 |
| Synonyms | NSC5844; NSC-5844; NSC 5844; RE640; RE-640; R E64 |
| Protocol | In Vitro | NSC5844 (Compound 10) is a 4-aminoquinoline derivative, and has antitumor activity with GI50s of 7.35 ± 0.10 μM and 14.80 ± 0.35 μM against MDA-MB-468 and MCF-7 cells, respectively. |
|---|
These protocols are for reference only. InvivoChem does not
independently validate these methods.
| Solvent volume to be added | Mass (the weight of a compound) | |||
|---|---|---|---|---|
| Mother liquor concentration | 1mg | 5mg | 10mg | 20mg |
| 1mM | 2.6091 mL | 13.0456 mL | 26.0913 mL | 52.1825 mL |
| 5mM | 0.5218 mL | 2.6091 mL | 5.2183 mL | 10.4365 mL |
| 10mM | 0.2609 mL | 1.3046 mL | 2.6091 mL | 5.2183 mL |
| 20mM | 0.1305 mL | 0.6523 mL | 1.3046 mL | 2.6091 mL |
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start)
×
Volume(start)
=
Concentration(final)
×
Volume(final)
This equation is commonly abbreviated as: C1 V1 = C2 V2
Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg
Average weight of animals g
Dosing volume per animal µL
Number of animals
Step Two: Enter the in vivo formulation
%DMSO
+
%
+
%Tween 80
+
%ddH2O
Calculation Results:
Working concentration:
mg/ml;
Method for preparing DMSO master liquid:
mg
drug pre-dissolved in
µL
DMSO(Master liquid concentration
mg/mL)
,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation:
Take
µL
DMSO master liquid, next add
µL
PEG300, mix and clarify, next add
µL
Tween 80,mix and clarify, next add
µL
ddH2O,mix and clarify.
Note:
- (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
- (2) Be sure to add the solvent(s) in order.