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Temocillin disodium salt

This product is for research use only, not for human use. We do not sell to patients.

Temocillin disodium salt
For small sizes, please check our retail website as below: www.invivochem.com
Size Price Stock
100mg$1235To Be Confirmed
200mg$1850To Be Confirmed
500mg$3120To Be Confirmed

Cat #: V40841 CAS #: 61545-06-0 Purity ≥ 99%

Description: Temocillin disodium salt is a semisynthetic, narrow-spectrum and β-lactamase-resistant penicillin introduced by Beecham, marketed by Eumedica Pharmaceuticals as Negaban.

References: K Jules, et al. Antibacterial activity and beta-lactamase stability of temocillin. Antimicrob Agents Chemother. 1982 Sep;22(3):453-60.

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Molecular Weight (MW)458.42
Molecular FormulaC16H16N2Na2O7S2
CAS No.61545-06-0
SynonymsTemocillin disodium salt
ProtocolIn VivoTemocillin dosing regimens of 200 mg/kg every 4 and 6 h remained significantly effective in reducing bacterial titres in kidneys against the two strains, with no significant difference between the parental strain and its transconjugant.
These protocols are for reference only. InvivoChem does not independently validate these methods.
Preparing Stock Solutions
Solvent volume to be added Mass (the weight of a compound)
Mother liquor concentration 1mg5mg10mg20mg
1mM2.1814 mL10.9070 mL21.8141 mL43.6281 mL
5mM0.4363 mL2.1814 mL4.3628 mL8.7256 mL
10mM0.2181 mL1.0907 mL2.1814 mL4.3628 mL
20mM0.1091 mL0.5454 mL1.0907 mL2.1814 mL
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start) × Volume(start) = Concentration(final) × Volume(final)

This equation is commonly abbreviated as: C1 V1 = C2 V2

Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals
Step Two: Enter the in vivo formulation
%DMSO + % + %Tween 80 + %ddH2O

Calculation Results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH2O,mix and clarify.
Note:
  • (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
  • (2) Be sure to add the solvent(s) in order.