Amdinocillin (Mecillinam; FL 1060)
This product is for research use only, not for human use. We do not sell to patients.
For small sizes, please check our retail website as below: www.invivochem.com
| Size | Price | Stock |
|---|---|---|
| 500mg | $450 | Check With Us |
| 1g | $750 | Check With Us |
| 5g | $1900 | Check With Us |
: Cat #: V6436 CAS #: 32887-01-7 Purity ≥ 99%
Description: Mecillinam (FL-1060; amdinocillin) is a potent and broad spectrum penicillin antibiotic that binds specifically to penicillin binding protein 2 (PBP2), and is only considered to be active against Gram-negative bacteria.
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| Molecular Weight (MW) | 325.43 |
|---|---|
| Molecular Formula | C15H23N3O3S |
| CAS No. | 32887-01-7 |
| SMILES Code | CC1(C(N2C(S1)C(C2=O)N=CN3CCCCCC3)C(=O)O)C |
| Synonyms | Hexacillin; FL 1060; FL-1060; FL1060; Mecillinam; AMDINOCILLIN; Coactin; Penicillin HX; Mecillinamum; |
| Protocol | In Vivo | Mecillinam (Amdinocillin, 400 mg per kg) is effective for the treatment of catheterassociated infections at high dosages (400 mg per kg of body weight/d). |
|---|
These protocols are for reference only. InvivoChem does not
independently validate these methods.
| Solvent volume to be added | Mass (the weight of a compound) | |||
|---|---|---|---|---|
| Mother liquor concentration | 1mg | 5mg | 10mg | 20mg |
| 1mM | 3.0729 mL | 15.3643 mL | 30.7286 mL | 61.4571 mL |
| 5mM | 0.6146 mL | 3.0729 mL | 6.1457 mL | 12.2914 mL |
| 10mM | 0.3073 mL | 1.5364 mL | 3.0729 mL | 6.1457 mL |
| 20mM | 0.1536 mL | 0.7682 mL | 1.5364 mL | 3.0729 mL |
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start)
×
Volume(start)
=
Concentration(final)
×
Volume(final)
This equation is commonly abbreviated as: C1 V1 = C2 V2
Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg
Average weight of animals g
Dosing volume per animal µL
Number of animals
Step Two: Enter the in vivo formulation
%DMSO
+
%
+
%Tween 80
+
%ddH2O
Calculation Results:
Working concentration:
mg/ml;
Method for preparing DMSO master liquid:
mg
drug pre-dissolved in
µL
DMSO(Master liquid concentration
mg/mL)
,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation:
Take
µL
DMSO master liquid, next add
µL
PEG300, mix and clarify, next add
µL
Tween 80,mix and clarify, next add
µL
ddH2O,mix and clarify.
Note:
- (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
- (2) Be sure to add the solvent(s) in order.