Capreomycin Sulfate

This product is for research use only, not for human use. We do not sell to patients.

For small sizes, please check our retail website as below: www.invivochem.com

Size	Price	Stock
2g	$350	Check With Us
5g	$600	Check With Us
10g	$900	Check With Us

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Cat #: V17497 CAS #: 1405-37-4 Purity ≥ 98%

Description: Capreomycin Sulfate (Capostatin; Kapreomycin), the sulfate salt of Capreomycin which is a naturally occurring and cyclic peptide antibiotic, acts as a ribosomal subunit inbihitor and used as an anti-tuberculosis/TB agent.

References: Johansen SK, et al. Capreomycin binds across the ribosomal subunit interface using tlyA-encoded 2'-O-methylations in 16S and 23S rRNAs. Mol Cell. 2006 Jul 21;23(2):173-82.

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Physicochemical and Storage Information
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Related Biological Data
Stock Solution Preparation
Quality Control Documentation

Molecular Weight (MW)	750.78
Molecular Formula	C25H46N14O11S
CAS No.	1405-37-4
SMILES Code	C[C@@H]1NC(=O)[C@@H](N)CNC(=O)[C@@H](NC(=O)\C(=C/NC(=O)N)\NC(=O)[C@H](CNC(=O)C[C@@H](N)CCCN)NC1=O)[C@H]2CCN=C(N)N2.NCCC[C@H](N)CC(=O)NC[C@@H]3NC(=O)[C@H](CO)NC(=O)[C@@H](N)CNC(=O)[C@@H](NC(=O)\C(=C/NC(=O)N)\NC3=O)[C@H]4CCN=C(N)N4.OS(=O)(=O)O.OS(=O)(=O)O
Synonyms	Capostatin; Capreomycin Sulfate; Kapreomycin;

Preparing Stock Solutions

Solvent volume to be added	Mass (the weight of a compound)
Mother liquor concentration	1mg	5mg	10mg	20mg
1mM	1.3319 mL	6.6597 mL	13.3195 mL	26.6390 mL
5mM	0.2664 mL	1.3319 mL	2.6639 mL	5.3278 mL
10mM	0.1332 mL	0.6660 mL	1.3319 mL	2.6639 mL
20mM	0.0666 mL	0.3330 mL	0.6660 mL	1.3319 mL

Quality Control Documentation	Select Batch Purity ≥ 98% COA MSDS NMR HPLC

The molarity calculator equation

Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)

Mass

Concentration

Volume

Molecular Weight*

The dilution calculator equation

Concentration_(start) × Volume_(start) = Concentration_(final) × Volume_(final)

This equation is commonly abbreviated as: C₁ V₁ = C₂ V₂

Concentration_(start)

Volume_(start)

Concentration_(final)

Volume_(final)

Step One: Enter information below

Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals

Step Two: Enter the in vivo formulation

%DMSO + % + %Tween 80 + %ddH₂O

Calculation Results:

Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.

Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH₂O,mix and clarify.

Note:

(1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
(2) Be sure to add the solvent(s) in order.