Kanamycin sulfate

This product is for research use only, not for human use. We do not sell to patients.

Kanamycin sulfate
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Size Price Stock
5g$345Check With Us
10g$600Check With Us
20g$900Check With Us

Cat #: V15297 CAS #: 25389-94-0 Purity ≥ 99%

Description: Kanamycin sulfate, the sulfate salt of Kanamycin (Kanamycin A; Kantrex; Kanamycine), is an aminoglycoside bacteriocidal antibiotic effective against gram-positive and negative bacteria and mycoplasma.

References: YANAGISAWA K, et al. Studies on kanamycin, a new antibiotic against tubercle bacilli. I. Effect on virulent tubercle bacilli in vitro and in mice. J Antibiot (Tokyo). 1957 Nov;10(6):233-5. 

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Molecular Weight (MW)582.58
Molecular FormulaC18H38N4O15S
CAS No.25389-94-0
SMILES CodeN[C@@H]1[C@@H](O[C@@H]2[C@H](O)[C@@H](O)[C@H](O)[C@@H](CN)O2)[C@H](O)[C@@H](O[C@@H]3[C@H](O)[C@@H](N)[C@H](O)[C@@H](CO)O3)[C@H](N)C1.OS(=O)(O)=O
SynonymsKanabristol; Kanacedi; Kanamycin sulfate; kanamycin A;
ProtocolIn VitroKanamycin sulfate (0.1-100 μg/mL; 2 weeks) exhibits good antibacterial activity (MIC=1-5 μg/mL) to various strains of mycobacteria in vitro.
In VivoKanamycin sulfate (2, 4 mg/kg; s.c.; once daily, 6 times a week for 3 weeks) inhibits growth of bovine tubercle bacilli in lung and spleen of mice.
These protocols are for reference only. InvivoChem does not independently validate these methods.
Preparing Stock Solutions
Solvent volume to be added Mass (the weight of a compound)
Mother liquor concentration 1mg5mg10mg20mg
1mM1.7165 mL8.5825 mL17.1650 mL34.3300 mL
5mM0.3433 mL1.7165 mL3.4330 mL6.8660 mL
10mM0.1717 mL0.8583 mL1.7165 mL3.4330 mL
20mM0.0858 mL0.4291 mL0.8583 mL1.7165 mL
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
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Concentration
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Volume
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Molecular Weight*
The dilution calculator equation
Concentration(start) × Volume(start) = Concentration(final) × Volume(final)

This equation is commonly abbreviated as: C1 V1 = C2 V2

Concentration(start)
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Volume(start)
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=
Concentration(final)
C2
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Volume(final)
V2
Step One: Enter information below
Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals
Step Two: Enter the in vivo formulation
%DMSO + % + %Tween 80 + %ddH2O

Calculation Results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH2O,mix and clarify.
Note:
  • (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
  • (2) Be sure to add the solvent(s) in order.