Triclocarban

This product is for research use only, not for human use. We do not sell to patients.

Triclocarban
For small sizes, please check our retail website as below: www.invivochem.com
Size Price Stock
10g$600To Be Confirmed
25g$1150To Be Confirmed
50g$1725To Be Confirmed

Cat #: V5238 CAS #: 101-20-2 Purity ≥ 98%

Description: Triclocarban (3,4,4′-Trichlorocarbanilide) is an antimicrobial / antibacterial compound that is widely used in personal cleaning / personal care products.

References: Kanbara Y, et al. Nanomolar concentration of triclocarban increases the vulnerability of rat thymocytes to oxidative stress. J Toxicol Sci. 2013 Feb;38(1):49-55.

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Product Promise

Promise
Molecular Weight (MW)315.58
Molecular FormulaC₁₃H₉Cl₃N₂O
CAS No.101-20-2
Storage-20℃ for 3 years in powder formr
-80℃ for 2 years in solvent
SMILES CodeO=C(NC1=CC=C(Cl)C=C1)NC2=CC=C(Cl)C(Cl)=C2
SynonymsTriclocarban
ProtocolIn VitroTriclocarban (300 nM) potentiates the cytotoxicity of 300 µM H2O2 in rat thymocytes. Triclocarban (300 nM) does not increase the population of death cells, it facilitates the process of cell death induced by H2O2, resulting in further increase in the population of dead cells.
In VivoTriclocarban is absorbed significantly from soap used during showering in human subjects and that its Cmax in their whole blood ranges from 23 nM to 530 nM.
These protocols are for reference only. InvivoChem does not independently validate these methods.
Preparing Stock Solutions
Solvent volume to be added Mass (the weight of a compound)
Mother liquor concentration 1mg5mg10mg20mg
1mM3.1688 mL15.8438 mL31.6877 mL63.3754 mL
5mM0.6338 mL3.1688 mL6.3375 mL12.6751 mL
10mM0.3169 mL1.5844 mL3.1688 mL6.3375 mL
20mM0.1584 mL0.7922 mL1.5844 mL3.1688 mL
Quality Control Documentation
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start) × Volume(start) = Concentration(final) × Volume(final)

This equation is commonly abbreviated as: C1 V1 = C2 V2

Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals
Step Two: Enter the in vivo formulation
%DMSO + % + %Tween 80 + %ddH2O

Calculation Results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH2O,mix and clarify.
Note:
  • (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
  • (2) Be sure to add the solvent(s) in order.