Azomycin (2-Nitroimidazole)

This product is for research use only, not for human use. We do not sell to patients.

For small sizes, please check our retail website as below: www.invivochem.com

Size	Price	Stock
5g	$250	Check With Us
10g	$450	Check With Us
20g	$675	Check With Us

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Cat #: V1979 CAS #: 527-73-1 Purity ≥ 98%

Description: Azomycin (2-Nitroimidazole) is an antimicrobial antibiotic extracted from a strain of Nocardia mesenterica and an unidentified Streptomyces. Azomycin is active against aerobic Gram-positive and Gram-negative bacteria. The structure of azomycinis a 2-nitroimidazole. Reduction of azomycin abolish the bacteriostatic activities. Also the closely related analog, 4-nitroimidazole does not exhibit bacteriostatic effects.

References: [1]. Shoji JH, et al. Isolation of azomycin from Pseudomonas fluorescens. J Antibiot (Tokyo). 1989 Oct;42(10):1513-4.

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Physicochemical and Storage Information
Protocol
Related Biological Data
Stock Solution Preparation
Quality Control Documentation

Molecular Weight (MW)	113.07
Molecular Formula	C3H3N3O2
CAS No.	527-73-1
Storage	-20℃ for 3 years in powder formr
Storage	-80℃ for 2 years in solvent
Solubility In Vitro	DMSO: > 10 mMr
	Water: NAr
	Ethanol: NA
SMILES Code	O=[N+]([O-])C1=NC=CN1
Synonyms	2-Nitroimidazole

Protocol	In Vitro	Azomycin is an antibiotic which can be active against aerobic Gram-positive and Gram-negative bacteria. It is found that Azomycin is also active against a variety of anaerobic bacteria.

These protocols are for reference only. InvivoChem does not independently validate these methods.

Preparing Stock Solutions

Solvent volume to be added	Mass (the weight of a compound)
Mother liquor concentration	1mg	5mg	10mg	20mg
1mM	8.8441 mL	44.2204 mL	88.4408 mL	176.8816 mL
5mM	1.7688 mL	8.8441 mL	17.6882 mL	35.3763 mL
10mM	0.8844 mL	4.4220 mL	8.8441 mL	17.6882 mL
20mM	0.4422 mL	2.2110 mL	4.4220 mL	8.8441 mL

Quality Control Documentation	Select Batch Purity ≥ 98% COA MSDS NMR HPLC

The molarity calculator equation

Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)

Mass

Concentration

Volume

Molecular Weight*

The dilution calculator equation

Concentration_(start) × Volume_(start) = Concentration_(final) × Volume_(final)

This equation is commonly abbreviated as: C₁ V₁ = C₂ V₂

Concentration_(start)

Volume_(start)

Concentration_(final)

Volume_(final)

Step One: Enter information below

Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals

Step Two: Enter the in vivo formulation

%DMSO + % + %Tween 80 + %ddH₂O

Calculation Results:

Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.

Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH₂O,mix and clarify.

Note:

(1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
(2) Be sure to add the solvent(s) in order.