Flucloxacillin sodium

This product is for research use only, not for human use. We do not sell to patients.

Flucloxacillin sodium
For small sizes, please check our retail website as below: www.invivochem.com
Size Price Stock
2g$550To Be Confirmed
5g$1050To Be Confirmed
10g$1575To Be Confirmed

Cat #: V21108 CAS #: 1847-24-1 Purity ≥ 99%

Description: Flucloxacillin sodium (Floxacillin, Floxapen) is a potent narrow-spectrum beta-lactam antibiotic used to treat infections caused by susceptible Gram-positive bacteria.

References: Greimel F, et, al. Efficacy of antibiotic treatment of implant-associated Staphylococcus aureus infections with moxifloxacin, flucloxacillin, rifampin, and combination therapy: an animal study. Drug Des Devel Ther. 2017 Jun 14;11:1729-1736.

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Molecular Weight (MW)475.85
Molecular FormulaC19H16ClFN3NaO5S
CAS No.1847-24-1
SMILES Code O=C([C@@H](C(C)(C)S[C@]1([H])[C@@H]2NC(C3=C(C)ON=C3C4=C(F)C=CC=C4Cl)=O)N1C2=O)[O-].[Na
SynonymsFloxapen, Fluorochloroxacillin, Flucloxacillin, Floxacillin,
ProtocolIn VivoFlucloxacillin sodium (200 mg/kg; i.p.; three times/day, for 21 days; male Wistar rats) has effective against the most common bacterial strains in periprosthetic infection.
Animal modelMale Wistar rats
These protocols are for reference only. InvivoChem does not independently validate these methods.
Preparing Stock Solutions
Solvent volume to be added Mass (the weight of a compound)
Mother liquor concentration 1mg5mg10mg20mg
1mM2.1015 mL10.5075 mL21.0150 mL42.0301 mL
5mM0.4203 mL2.1015 mL4.2030 mL8.4060 mL
10mM0.2102 mL1.0508 mL2.1015 mL4.2030 mL
20mM0.1051 mL0.5254 mL1.0508 mL2.1015 mL
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
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Concentration
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Volume
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Molecular Weight*
The dilution calculator equation
Concentration(start) × Volume(start) = Concentration(final) × Volume(final)

This equation is commonly abbreviated as: C1 V1 = C2 V2

Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
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Volume(final)
V2
Step One: Enter information below
Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals
Step Two: Enter the in vivo formulation
%DMSO + % + %Tween 80 + %ddH2O

Calculation Results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH2O,mix and clarify.
Note:
  • (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
  • (2) Be sure to add the solvent(s) in order.