Dicloxacillin sodium

This product is for research use only, not for human use. We do not sell to patients.

For small sizes, please check our retail website as below: www.invivochem.com

Size	Price	Stock
2g	$725	To Be Confirmed
5g	$1350	To Be Confirmed
10g	$2025	To Be Confirmed

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Cat #: V5308 CAS #: 13412-64-1 Purity ≥ 98%

Description: Dicloxacillin Sodium is an orally bioactive, narrow-spectrum and semisynthetic isoxazolyl antistaphylococcal and narrow-spectrum β-Lactam antibiotic of the penicillin class, it is used to treat infections caused by susceptible Gram-positive bacteria, active against beta-lactamase-producing organisms such as Staphylococcus aureus.

References: Miranda-Novales G, et al. In vitro activity effects of combinations of cephalothin, dicloxacillin, imipenem, vancomycin and amikacin against methicillin-resistant Staphylococcus spp. strains. Ann Clin Microbiol Antimicrob. 2006 Oct 12;5:25.

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Physicochemical and Storage Information
Protocol
Related Biological Data
Stock Solution Preparation
Quality Control Documentation

Molecular Weight (MW)	492.31
Molecular Formula	C19H16Cl2N3NaO5S
CAS No.	13412-64-1
Storage	-20℃ for 3 years in powder formr
Storage	-80℃ for 2 years in solvent
SMILES Code	O=C([C@@H](C(C)(C)S[C@]1([H])[C@@H]2NC(C3=C(C)ON=C3C4=C(Cl)C=CC=C4Cl)=O)N1C2=O)[O-].[H]O[H].[Na+]
Synonyms	Dicloxacillin sodium; BLP-1011; BRL-1702; P 1011; P-1011; P1011; MDI-PC

Protocol	In Vitro	Dicloxacillin exhibits EC50 values of 0.06 and 0.50 mg/L in ATCC 25923 and E19977, respectively. Dicloxacillin exhibits MIC values of 0.125 and 0.5 mg/L in ATCC 25923 and E19977 with pH 7.4, respectively.
Protocol	In Vivo	Dicloxacillin exhibits therapeutic activity in murine peritonitis-sepsis model and all the mice are survivied.

These protocols are for reference only. InvivoChem does not independently validate these methods.

Preparing Stock Solutions

Solvent volume to be added	Mass (the weight of a compound)
Mother liquor concentration	1mg	5mg	10mg	20mg
1mM	2.0312 mL	10.1562 mL	20.3124 mL	40.6248 mL
5mM	0.4062 mL	2.0312 mL	4.0625 mL	8.1250 mL
10mM	0.2031 mL	1.0156 mL	2.0312 mL	4.0625 mL
20mM	0.1016 mL	0.5078 mL	1.0156 mL	2.0312 mL

Quality Control Documentation	Select Batch Purity ≥ 98% COA MSDS NMR HPLC

The molarity calculator equation

Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)

Mass

Concentration

Volume

Molecular Weight*

The dilution calculator equation

Concentration_(start) × Volume_(start) = Concentration_(final) × Volume_(final)

This equation is commonly abbreviated as: C₁ V₁ = C₂ V₂

Concentration_(start)

Volume_(start)

Concentration_(final)

Volume_(final)

Step One: Enter information below

Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals

Step Two: Enter the in vivo formulation

%DMSO + % + %Tween 80 + %ddH₂O

Calculation Results:

Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.

Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH₂O,mix and clarify.

Note:

(1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
(2) Be sure to add the solvent(s) in order.