Brodimoprim | CAS 56518-41-3

Brodimoprim

This product is for research use only, not for human use. We do not sell to patients.

For small sizes, please check our retail website as below: www.invivochem.com

Size	Price	Stock
100mg	$1275	To Be Confirmed
200mg	$1910	To Be Confirmed
500mg	$3225	To Be Confirmed

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Cat #: V17059 CAS #: 56518-41-3 Purity ≥ 99%

Description: Brodimoprim (Ro-105970) is an analogue of trimethoprim and is an orally bioactive and long-acting DHFR/dihydrofolate reductase inhibitor with activity against a broad spectrum of gram-negative and gram-positive bacteria.

References: Weidekamm E. Pharmacokinetics of brodimoprim. J Chemother. 1993;5(6):475-479.

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Molecular Weight (MW)	339.19
Molecular Formula	C13H15BrN4O2
CAS No.	56518-41-3
SMILES Code	COC1=C(Br)C(OC)=CC(CC2=CN=C(N)N=C2N)=C1
Synonyms	Brodimoprim

Preparing Stock Solutions

Solvent volume to be added	Mass (the weight of a compound)
Mother liquor concentration	1mg	5mg	10mg	20mg
1mM	2.9482 mL	14.7410 mL	29.4820 mL	58.9640 mL
5mM	0.5896 mL	2.9482 mL	5.8964 mL	11.7928 mL
10mM	0.2948 mL	1.4741 mL	2.9482 mL	5.8964 mL
20mM	0.1474 mL	0.7371 mL	1.4741 mL	2.9482 mL

The molarity calculator equation

Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)

Mass

Concentration

Volume

Molecular Weight*

The dilution calculator equation

Concentration_(start) × Volume_(start) = Concentration_(final) × Volume_(final)

This equation is commonly abbreviated as: C₁ V₁ = C₂ V₂

Concentration_(start)

Volume_(start)

Concentration_(final)

Volume_(final)

Step One: Enter information below

Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals

Step Two: Enter the in vivo formulation

%DMSO + % + %Tween 80 + %ddH₂O

Calculation Results:

Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.

Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH₂O,mix and clarify.

Note:

(1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
(2) Be sure to add the solvent(s) in order.