Fosfomycin sodium
This product is for research use only, not for human use. We do not sell to patients.
For small sizes, please check our retail website as below: www.invivochem.com
| Size | Price | Stock |
|---|---|---|
| 5g | $120 | In Stock |
| 10g | $160 | In Stock |
| 20g | $240 | In Stock |
: Cat #: V2507 CAS #: 26016-99-9 Purity ≥ 99%
Description: Fosfomycin sodium(also known as MK-955) is an antibiotic. USP grade with 720IU/mg
References: Falagas ME, et al. Fosfomycin. Clin Microbiol Rev. 2016 Apr. 29(2):321-47.
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- Physicochemical and Storage Information
- Protocol
- Related Biological Data
- Stock Solution Preparation
- Quality Control Documentation
| Molecular Weight (MW) | 182.02 |
|---|---|
| Molecular Formula | C3H5Na2O4P |
| CAS No. | 26016-99-9 |
| SMILES Code | [Na+].[Na+].C[C@@H]1O[C@@H]1P(=O)([O-])[O-] |
| Synonyms | Disodium phosphonomycin; Disodium fosfomycin; Forocyle S; MK955; MK 955; MK-955; Phosphonomycin disodium salt ; Fosfomycin sodium |
| Protocol | In Vitro | Fosfomycin sodium is an epoxy antibacterial agent. Compared with other antibacterial agents, it acts by inhibiting the early process of cell wall synthesis. |
|---|---|---|
| In Vivo | Fosfomycin sodium (80 mg/kg; i.v.-i.v. or i.v.-p.o.) displays the protective effect on the nephrotoxicity of double beckacin, and is not affected by different administration routes. | |
| Animal model | Fischer 344 rats | |
| Dosages | 320 mg/kg | |
| Administration | Intramuscular injection, 5 schedules: 1 h, 0.5 h earlier than dibekacin, concomitantly, 0.5 h later and 1 h later; 11 days |
These protocols are for reference only. InvivoChem does not
independently validate these methods.
| Solvent volume to be added | Mass (the weight of a compound) | |||
|---|---|---|---|---|
| Mother liquor concentration | 1mg | 5mg | 10mg | 20mg |
| 1mM | 5.4939 mL | 27.4695 mL | 54.9390 mL | 109.8780 mL |
| 5mM | 1.0988 mL | 5.4939 mL | 10.9878 mL | 21.9756 mL |
| 10mM | 0.5494 mL | 2.7470 mL | 5.4939 mL | 10.9878 mL |
| 20mM | 0.2747 mL | 1.3735 mL | 2.7470 mL | 5.4939 mL |
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start)
×
Volume(start)
=
Concentration(final)
×
Volume(final)
This equation is commonly abbreviated as: C1 V1 = C2 V2
Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg
Average weight of animals g
Dosing volume per animal µL
Number of animals
Step Two: Enter the in vivo formulation
%DMSO
+
%
+
%Tween 80
+
%ddH2O
Calculation Results:
Working concentration:
mg/ml;
Method for preparing DMSO master liquid:
mg
drug pre-dissolved in
µL
DMSO(Master liquid concentration
mg/mL)
,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation:
Take
µL
DMSO master liquid, next add
µL
PEG300, mix and clarify, next add
µL
Tween 80,mix and clarify, next add
µL
ddH2O,mix and clarify.
Note:
- (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
- (2) Be sure to add the solvent(s) in order.