Lefamulin acetate (BC-3781 acetate)
This product is for research use only, not for human use. We do not sell to patients.
For small sizes, please check our retail website as below: www.invivochem.com
| Size | Price | Stock |
|---|---|---|
| 1g | $600 | Check With Us |
| 5g | $950 | Check With Us |
| 10g | $1425 | Check With Us |
: Cat #: V9171 CAS #: 1350636-82-6 Purity ≥ 98%
Description: Lefamulin acetate (formerly BC3781; Xenleta), the acetate salt form of lefamulin, is a semi-synthetic, orally bioactive pleuromutilin antibiotic that acts as an inhibitor for the synthesis of bacterial protein.
Top Publications Citing Invivochem Products
Publications Citing InvivoChem Products
Product Promise
- Physicochemical and Storage Information
- Protocol
- Related Biological Data
- Stock Solution Preparation
- Quality Control Documentation
| Molecular Weight (MW) | 567.78 |
|---|---|
| Molecular Formula | C30H49NO7S |
| CAS No. | 1350636-82-6 |
| SMILES Code | CC(O)=O.O=C(O[C@@H]1C[C@](C=C)(C)[C@@H](O)[C@H](C)[C@]2(CCC3=O)[C@]3([H])[C@@]1(C)[C@H](C)CC2)CS[C@H]4[C@H](O)C[C@H](N)CC4 |
| Synonyms | Lefamulin acetate; BC-3781.Ac; BC 3781.Ac; BC3781.Ac; BC-3781; BC 3781; BC3781; Xenleta; |
| Protocol | In Vitro | Lefamulin (0-1 mg/L) acetate shows inhibitory activity against C. trachomatis, N. gonorrhoeae, and M. genitalium. |
|---|---|---|
| In Vivo | Lefamulin (10-140 mg/kg, s.c.) acetate shows anti-inflammatory effect on LPS-induced lung neutrophilia mouse model. |
These protocols are for reference only. InvivoChem does not
independently validate these methods.
| Solvent volume to be added | Mass (the weight of a compound) | |||
|---|---|---|---|---|
| Mother liquor concentration | 1mg | 5mg | 10mg | 20mg |
| 1mM | 1.7612 mL | 8.8062 mL | 17.6125 mL | 35.2249 mL |
| 5mM | 0.3522 mL | 1.7612 mL | 3.5225 mL | 7.0450 mL |
| 10mM | 0.1761 mL | 0.8806 mL | 1.7612 mL | 3.5225 mL |
| 20mM | 0.0881 mL | 0.4403 mL | 0.8806 mL | 1.7612 mL |
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start)
×
Volume(start)
=
Concentration(final)
×
Volume(final)
This equation is commonly abbreviated as: C1 V1 = C2 V2
Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg
Average weight of animals g
Dosing volume per animal µL
Number of animals
Step Two: Enter the in vivo formulation
%DMSO
+
%
+
%Tween 80
+
%ddH2O
Calculation Results:
Working concentration:
mg/ml;
Method for preparing DMSO master liquid:
mg
drug pre-dissolved in
µL
DMSO(Master liquid concentration
mg/mL)
,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation:
Take
µL
DMSO master liquid, next add
µL
PEG300, mix and clarify, next add
µL
Tween 80,mix and clarify, next add
µL
ddH2O,mix and clarify.
Note:
- (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
- (2) Be sure to add the solvent(s) in order.