Valinomycin (NSC-122023)

This product is for research use only, not for human use. We do not sell to patients.

For small sizes, please check our retail website as below: www.invivochem.com

Size	Price	Stock
500mg	$1450	To Be Confirmed
1g	$2350	To Be Confirmed
5g	$7930	To Be Confirmed

: [email protected] [email protected]

Cat #: V5044 CAS #: 2001-95-8 Purity ≥ 98%

Description: Valinomycin (formerly known a NSC 122023) is a novel and potent cyclic depsipeptide antibiotic originally isolated from Streptomyces fulvissimus, it acts as a potassium selective ionophore.

References: Daniele RP, et al. A potassium ionophore (valinomycin) inhibits lymphocyte proliferation by its effects on the cell membrane. Proc Natl Acad Sci U S A. 1976 Oct;73(10):3599-602.

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Physicochemical and Storage Information
Protocol
Related Biological Data
Stock Solution Preparation
Quality Control Documentation

Molecular Weight (MW)	1111.32
Molecular Formula	C54H90N6O18
CAS No.	2001-95-8
Storage	-20℃ for 3 years in powder formr
Storage	-80℃ for 2 years in solvent
SMILES Code	O=C([C@@H](C(C)C)NC([C@@H](C(C)C)OC([C@H](C(C)C)NC([C@H](C)OC([C@@H](C(C)C)NC([C@@H](C(C)C)OC([C@H](C(C)C)NC([C@H](C)OC([C@@H](C(C)C)NC([C@@H](C(C)C)OC([C@H](C(C)C)N1)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)O[C@@H](C)C1=O
Synonyms	Valinomycin; NSC 122023; NSC-122023; NSC122023

Preparing Stock Solutions

Solvent volume to be added	Mass (the weight of a compound)
Mother liquor concentration	1mg	5mg	10mg	20mg
1mM	0.8998 mL	4.4992 mL	8.9983 mL	17.9966 mL
5mM	0.1800 mL	0.8998 mL	1.7997 mL	3.5993 mL
10mM	0.0900 mL	0.4499 mL	0.8998 mL	1.7997 mL
20mM	0.0450 mL	0.2250 mL	0.4499 mL	0.8998 mL

Quality Control Documentation	Select Batch Purity ≥ 98% COA MSDS NMR HPLC

The molarity calculator equation

Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)

Mass

Concentration

Volume

Molecular Weight*

The dilution calculator equation

Concentration_(start) × Volume_(start) = Concentration_(final) × Volume_(final)

This equation is commonly abbreviated as: C₁ V₁ = C₂ V₂

Concentration_(start)

Volume_(start)

Concentration_(final)

Volume_(final)

Step One: Enter information below

Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals

Step Two: Enter the in vivo formulation

%DMSO + % + %Tween 80 + %ddH₂O

Calculation Results:

Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.

Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH₂O,mix and clarify.

Note:

(1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
(2) Be sure to add the solvent(s) in order.