Cinoxacin (Cinobac; Compound 64716)
This product is for research use only, not for human use. We do not sell to patients.
For small sizes, please check our retail website as below: www.invivochem.com
| Size | Price | Stock |
|---|---|---|
| 500mg | $300 | Check With Us |
| 1g | $450 | Check With Us |
| 5g | $1140 | Check With Us |
: Cat #: V18362 CAS #: 28657-80-9 Purity ≥ 98%
Description: Cinoxacin (Cinobac; Compound 64716) was a synthetic antimicrobial agent for oral administration.
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- Physicochemical and Storage Information
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- Related Biological Data
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| Molecular Weight (MW) | 262.22 |
|---|---|
| Molecular Formula | C12H10N2O5 |
| CAS No. | 28657-80-9 |
| SMILES Code | CCN1C2=CC3=C(C=C2C(=O)C(=N1)C(=O)O)OCO3 |
| Synonyms | Cinoxacinum;Acid, Azolinic; Azolinic Acid; Cinoxacin; Cinobac; Compound 64716; Cinoxacine; Cinoxacino; |
| Protocol | In Vitro | Cinoxacin (0-200μg/mL approximately, 3-24 h) inhibits many gram-negative aerobic bacteria with MIC values ranging from 4 to 64 μg/mL. |
|---|---|---|
| In Vivo | Cinoxacin (Oral administration, 1.7 g/kg, treated at 1 and 5 h postinfection) is effective in experimental bacterial infections in mice, with ED50 values ranging from 8.1 to 58.6 mg/kg. |
These protocols are for reference only. InvivoChem does not
independently validate these methods.
| Solvent volume to be added | Mass (the weight of a compound) | |||
|---|---|---|---|---|
| Mother liquor concentration | 1mg | 5mg | 10mg | 20mg |
| 1mM | 3.8136 mL | 19.0680 mL | 38.1359 mL | 76.2718 mL |
| 5mM | 0.7627 mL | 3.8136 mL | 7.6272 mL | 15.2544 mL |
| 10mM | 0.3814 mL | 1.9068 mL | 3.8136 mL | 7.6272 mL |
| 20mM | 0.1907 mL | 0.9534 mL | 1.9068 mL | 3.8136 mL |
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start)
×
Volume(start)
=
Concentration(final)
×
Volume(final)
This equation is commonly abbreviated as: C1 V1 = C2 V2
Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg
Average weight of animals g
Dosing volume per animal µL
Number of animals
Step Two: Enter the in vivo formulation
%DMSO
+
%
+
%Tween 80
+
%ddH2O
Calculation Results:
Working concentration:
mg/ml;
Method for preparing DMSO master liquid:
mg
drug pre-dissolved in
µL
DMSO(Master liquid concentration
mg/mL)
,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation:
Take
µL
DMSO master liquid, next add
µL
PEG300, mix and clarify, next add
µL
Tween 80,mix and clarify, next add
µL
ddH2O,mix and clarify.
Note:
- (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
- (2) Be sure to add the solvent(s) in order.