LED209

This product is for research use only, not for human use. We do not sell to patients.

LED209
For small sizes, please check our retail website as below: www.invivochem.com
Size Price Stock
100mg$600Check With Us
250mg$1100Check With Us
500mg$1650Check With Us

Cat #: V12076 CAS #: 245342-14-7 Purity ≥ 98%

Description: LED209 is a novel non-toxic inhibitor of the binding signals to QseC, preventing its autophosphorylation and consequently inhibiting QseC-mediated activation of virulence gene expression.

References: Curtis MM, et al. QseC inhibitors as an antivirulence approach for Gram-negative pathogens. MBio. 2014 Nov 11;5(6):e02165.

Top Publications Citing Invivochem Products
Publications Citing InvivoChem Products

Product Promise

Promise
Molecular Weight (MW)383.49
Molecular FormulaC19H17N3O2S2
CAS No.245342-14-7
SMILES CodeS=C(NC1=CC=C(S(=O)(NC2=CC=CC=C2)=O)C=C1)NC3=CC=CC=C3
SynonymsLED 209; LED-209; LED209
Preparing Stock Solutions
Solvent volume to be added Mass (the weight of a compound)
Mother liquor concentration 1mg5mg10mg20mg
1mM2.6076 mL13.0381 mL26.0763 mL52.1526 mL
5mM0.5215 mL2.6076 mL5.2153 mL10.4305 mL
10mM0.2608 mL1.3038 mL2.6076 mL5.2153 mL
20mM0.1304 mL0.6519 mL1.3038 mL2.6076 mL
Quality Control Documentation
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start) × Volume(start) = Concentration(final) × Volume(final)

This equation is commonly abbreviated as: C1 V1 = C2 V2

Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals
Step Two: Enter the in vivo formulation
%DMSO + % + %Tween 80 + %ddH2O

Calculation Results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH2O,mix and clarify.
Note:
  • (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
  • (2) Be sure to add the solvent(s) in order.