Amoxicillin Trihydrate (Amoxycillin)

This product is for research use only, not for human use. We do not sell to patients.

For small sizes, please check our retail website as below: www.invivochem.com

Size	Price	Stock
50g	$320	Check With Us
100g	$550	Check With Us
200g	$825	Check With Us

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Cat #: V11208 CAS #: 61336-70-7 Purity ≥ 98%

Description: Amoxicillin Trihydrate (Amoxycillin), a potent, broad-spectrum, bacteriolytic, orally bioactive β-lactam antibiotic of the penicillin class, is widely used to treat various bacterial infections, including bronchitis, pneumonia, and infections of the ear, nose, throat, skin, and urinary tract.

References: Guo Y, et, al. Metabolic response of Lactobacillus acidophilus exposed to amoxicillin. J Antibiot (Tokyo). 2022 May;75(5):268-281.

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Physicochemical and Storage Information
Protocol
Related Biological Data
Stock Solution Preparation
Quality Control Documentation

Molecular Weight (MW)	419.45
Molecular Formula	C16H25N3O8S
CAS No.	61336-70-7
SMILES Code	O=C([C@@H](C(C)(C)S[C@]1([H])[C@@H]2NC([C@H](N)C3=CC=C(O)C=C3)=O)N1C2=O)O.[H]O[H].[H]O[H].[H]O[H]
Synonyms	Amoxicillin Trihydrate; Amoxicillin 3H2O; Larotid; Amoxil; Amoxipen; Moxaline; Amodex;

Protocol	In Vitro	Amoxicillin (Amoxycillin) trihydrate (1-100 µM; 24 hours; L. acidophilus) decreases living cells and increases degree of cell wall rupture in a dose-dependent manner.
Protocol	In Vivo	Amoxicillin (Amoxycillin) trihydrate (7 mg/kg; i.h.; female ICR/Swiss mice) inhibits strain numbers and improves the survival rate of rats in 1 mg/L or less.

These protocols are for reference only. InvivoChem does not independently validate these methods.

Preparing Stock Solutions

Solvent volume to be added	Mass (the weight of a compound)
Mother liquor concentration	1mg	5mg	10mg	20mg
1mM	2.3841 mL	11.9204 mL	23.8407 mL	47.6815 mL
5mM	0.4768 mL	2.3841 mL	4.7681 mL	9.5363 mL
10mM	0.2384 mL	1.1920 mL	2.3841 mL	4.7681 mL
20mM	0.1192 mL	0.5960 mL	1.1920 mL	2.3841 mL

Quality Control Documentation	Select Batch Purity ≥ 98% COA MSDS NMR HPLC

The molarity calculator equation

Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)

Mass

Concentration

Volume

Molecular Weight*

The dilution calculator equation

Concentration_(start) × Volume_(start) = Concentration_(final) × Volume_(final)

This equation is commonly abbreviated as: C₁ V₁ = C₂ V₂

Concentration_(start)

Volume_(start)

Concentration_(final)

Volume_(final)

Step One: Enter information below

Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals

Step Two: Enter the in vivo formulation

%DMSO + % + %Tween 80 + %ddH₂O

Calculation Results:

Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.

Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH₂O,mix and clarify.

Note:

(1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
(2) Be sure to add the solvent(s) in order.