Vancomycin

This product is for research use only, not for human use. We do not sell to patients.

Vancomycin
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Size Price Stock
25g$588Check With Us
50g$880Check With Us
100g$1320Check With Us

Cat #: V32969 CAS #: 1404-90-6 Purity ≥ 98%

Description: Vancomycin (Lyphocin) is a narrow-spectrum amphoteric glycopeptide antibacterial drug used to treat a number of bacterial infections.

References: Rybak MJ, et al. The pharmacokinetic and pharmacodynamic properties of vancomycin. Clin Infect Dis. 2006 Jan 1;42 Suppl 1:S35-9.

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Molecular Weight (MW)1449.25
Molecular FormulaC66H75Cl2N9O24
CAS No.1404-90-6
SynonymsVancomycin
ProtocolIn VitroVancomycin is a large glycopeptide compound with a molecular weight of 1450 Da.
In VivoVancomycin is administered intravenously, with a standard infusion time of at least 1 h, to minimize infusion-related adverse effects. Subjects with normal creatinine clearance, vancomycin has an α-distribution phase of 30 min to 1 h and a β-elimination half-life of 6-12 h. The volume of distribution is 0.4–1 L/kg. The binding of vancomycin to protein ranges from 10% to 50%. Factors that affect the overall activity of vancomycin include its tissue distribution, inoculum size, and protein-binding effects.
These protocols are for reference only. InvivoChem does not independently validate these methods.
Preparing Stock Solutions
Solvent volume to be added Mass (the weight of a compound)
Mother liquor concentration 1mg5mg10mg20mg
1mM0.6900 mL3.4501 mL6.9001 mL13.8002 mL
5mM0.1380 mL0.6900 mL1.3800 mL2.7600 mL
10mM0.0690 mL0.3450 mL0.6900 mL1.3800 mL
20mM0.0345 mL0.1725 mL0.3450 mL0.6900 mL
Quality Control Documentation
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start) × Volume(start) = Concentration(final) × Volume(final)

This equation is commonly abbreviated as: C1 V1 = C2 V2

Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals
Step Two: Enter the in vivo formulation
%DMSO + % + %Tween 80 + %ddH2O

Calculation Results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH2O,mix and clarify.
Note:
  • (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
  • (2) Be sure to add the solvent(s) in order.