Temafloxacin (Omniflox)
This product is for research use only, not for human use. We do not sell to patients.
For small sizes, please check our retail website as below: www.invivochem.com
| Size | Price | Stock |
|---|---|---|
| 100mg | $1750 | To Be Confirmed |
| 250mg | $2950 | To Be Confirmed |
| 500mg | $4425 | To Be Confirmed |
: Cat #: V5127 CAS #: 108319-06-8 Purity ≥ 98%
Description: Temafloxacin (Omniflox) is a potent fluoroquinolone antibiotic and antimycobacterial agent that acts as a DNA topoisomerase inhibitor.
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- Physicochemical and Storage Information
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- Related Biological Data
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| Molecular Weight (MW) | 417.38 |
|---|---|
| Molecular Formula | C21H18F3N3O3 |
| CAS No. | 108319-06-8 |
| Storage | -20℃ for 3 years in powder formr |
| -80℃ for 2 years in solvent | |
| SMILES Code | O=C(C1=CN(C2=CC=C(F)C=C2F)C3=C(C=C(F)C(N4CC(C)NCC4)=C3)C1=O)O |
| Synonyms | Temafloxacin; Omniflox; |
| Protocol | In Vitro | Temafloxacin (0-64 µg/mL; 18-24 h) shows good antibacterial activity for gram-positive/negative bacteria, with MIC ranges of <0.004-0.5, 0.5-2 and 0.06-0.25 µg/mL for E. coli, P. aeruginosa, and S. aureus, respectively. |
|---|---|---|
| In Vivo | Temafloxacin hydrochloride (100 mg/kg; p.o. or s.c.; single) shows rapid gastrointestinal absorption, and has excellent tissue and body fluid penetration and concentration (except for central nervous system (CNS)). Temafloxacin (6.25, 25, 100 mg/kg; p.o.; single) shows good inhibitory activity to murine pyelonephritis. |
These protocols are for reference only. InvivoChem does not
independently validate these methods.
| Solvent volume to be added | Mass (the weight of a compound) | |||
|---|---|---|---|---|
| Mother liquor concentration | 1mg | 5mg | 10mg | 20mg |
| 1mM | 2.3959 mL | 11.9795 mL | 23.9590 mL | 47.9180 mL |
| 5mM | 0.4792 mL | 2.3959 mL | 4.7918 mL | 9.5836 mL |
| 10mM | 0.2396 mL | 1.1979 mL | 2.3959 mL | 4.7918 mL |
| 20mM | 0.1198 mL | 0.5990 mL | 1.1979 mL | 2.3959 mL |
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start)
×
Volume(start)
=
Concentration(final)
×
Volume(final)
This equation is commonly abbreviated as: C1 V1 = C2 V2
Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg
Average weight of animals g
Dosing volume per animal µL
Number of animals
Step Two: Enter the in vivo formulation
%DMSO
+
%
+
%Tween 80
+
%ddH2O
Calculation Results:
Working concentration:
mg/ml;
Method for preparing DMSO master liquid:
mg
drug pre-dissolved in
µL
DMSO(Master liquid concentration
mg/mL)
,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation:
Take
µL
DMSO master liquid, next add
µL
PEG300, mix and clarify, next add
µL
Tween 80,mix and clarify, next add
µL
ddH2O,mix and clarify.
Note:
- (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
- (2) Be sure to add the solvent(s) in order.