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| Size | Price | Stock |
|---|---|---|
| 250mg | $625 | Check With Us |
| 500mg | $845 | Check With Us |
| 1g | $1265 | Check With Us |
: Cat #: V2103 CAS #: 163253-35-8 Purity ≥ 98%
Description: Sitafloxacin 1.5Hydrate (DU-6859a), a new-generation, broad-spectrum and oral fluoroquinolone class of antibiotic, is highly active against many Gram-positive, Gram-negative and anaerobic clinical isolates, including strains resistant to other fluoroquinolones, was recently approved in Japan for the treatment of respiratory and urinary tract infections. In terms of clinical efficacy, oral sitafloxacin was noninferior to oral levofloxacin in the treatment of community-acquired pneumonia or an infectious exacerbation of chronic respiratory tract disease, noninferior to oral tosufloxacin in the treatment of community-acquired pneumonia, and noninferior to oral levofloxacin in the treatment of complicated urinary tract infections, according to the results of randomized, double-blind, multicentre, noninferiority trials. Noncomparative studies demonstrated the efficacy of oral sitafloxacin in otorhinolaryngological infections, urethritis in men, C. trachomatis-associated cervicitis in women and odontogenic infections.
References: [1]. Anderson, D.L., Sitafloxacin hydrate for bacterial infections. Drugs Today (Barc), 2008. 44(7): p. 489-501.
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- Physicochemical and Storage Information
- Protocol
- Related Biological Data
- Stock Solution Preparation
- Quality Control Documentation
| Molecular Weight (MW) | 436.84 |
|---|---|
| Molecular Formula | C19H18ClF2N3O3.3/2H2O |
| CAS No. | 163253-35-8 |
| Storage | -20℃ for 3 years in powder formr |
| -80℃ for 2 years in solvent | |
| Solubility In Vitro | DMSO: 4 mg/mL (9.2 mM)r |
| Water: <1 mg/mLr | |
| Ethanol: <1 mg/mL | |
| SMILES Code | O=C(C1=CN([C@H]2[C@@H](F)C2)C3=C(C=C(F)C(N(C[C@H]4N)CC54CC5)=C3Cl)C1=O)O.O=C(C6=CN([C@H]7[C@@H](F)C7)C8=C(C=C(F)C(N(C[C@H]9N)CC%109CC%10)=C8Cl)C6=O)O.[H]O[H].[H]O[H].[H]O[H] |
| Synonyms | DU-6859a; DU 6859; DU-6859; DU6859; DU 6859A; DU-6859A; DU6859A; Sitafloxacin; Sitafloxacin hydrate, Sitafloxacin anhydrous, Gracevit. |
| Solvent volume to be added | Mass (the weight of a compound) | |||
|---|---|---|---|---|
| Mother liquor concentration | 1mg | 5mg | 10mg | 20mg |
| 1mM | 2.2892 mL | 11.4458 mL | 22.8917 mL | 45.7834 mL |
| 5mM | 0.4578 mL | 2.2892 mL | 4.5783 mL | 9.1567 mL |
| 10mM | 0.2289 mL | 1.1446 mL | 2.2892 mL | 4.5783 mL |
| 20mM | 0.1145 mL | 0.5723 mL | 1.1446 mL | 2.2892 mL |
This equation is commonly abbreviated as: C1 V1 = C2 V2
- (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
- (2) Be sure to add the solvent(s) in order.