This product is for research use only, not for human use. We do not sell to patients.
| Size | Price | Stock |
|---|---|---|
| 100g | $550 | Check With Us |
| 200g | $900 | Check With Us |
| 1μg | $1500 | Check With Us |
: Cat #: V2058 CAS #: 34642-77-8 Purity ≥ 98%
Description: Amoxicillin Sodium (Amoxycillin), a potent, moderate-spectrum, bacteriolytic, orally bioactive β-lactam antibiotic of the penicillin class, is widely used to treat various bacterial infections, including bronchitis, pneumonia, and infections of the ear, nose, throat, skin, and urinary tract. Though it can be highly effective in treating bacterial infections, it also comes with a list of potential side effects. It inhibits bacterial cell wall biosynthesis by preventing peptidoglycan cross-linking. Shows bacteriocidal effects against gram-positive and gram-negative species in vivo. Amoxicillin is often times combined with Clavulanic acid is a β-lactam drug that functions as a mechanism-based β-Lactamase inhibitor.
References: [1]. Guo Y, et, al. Metabolic response of Lactobacillus acidophilus exposed to amoxicillin. J Antibiot (Tokyo). 2022 May;75(5):268-281.
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- Physicochemical and Storage Information
- Protocol
- Related Biological Data
- Stock Solution Preparation
- Quality Control Documentation
| Molecular Weight (MW) | 387.39 |
|---|---|
| Molecular Formula | C16H18N3O5S.Na |
| CAS No. | 34642-77-8 |
| Storage | -20℃ for 3 years in powder formr |
| -80℃ for 2 years in solvent | |
| Solubility In Vitro | DMSO: 78 mg/mL (201.3 mM)r |
| Water: <1 mg/mLr | |
| Ethanol: 78 mg/mL (201.3 mM) | |
| SMILES Code | O=C([C@@H](C(C)(C)S[C@]1([H])[C@@H]2NC(C(N)C3=CC=C(O)C=C3)=O)N1C2=O)[O-].[Na+] |
| Synonyms | Clavulanate; Amoxicillin sodium; Lamoxy; Penamox; BRL-2333AB-B; Moxacin; |
| Protocol | In Vitro | Amoxicillin (Amoxycillin) sodium (1-100 µM; 24 hours; L. acidophilus) decreases living cells and increases degree of cell wall rupture in a dose-dependent manner. |
|---|---|---|
| In Vivo | Amoxicillin (Amoxycillin) sodium (7 mg/kg; i.h.; female ICR/Swiss mice) inhibits strain numbers and improves the survival rate of rats in 1 mg/L or less. | |
| Animal model | Female ICR/Swiss mice | |
| Dosages | 7 mg/kg | |
| Administration | Subcutaneous injection; every 8 h, for 24 hours |
| Solvent volume to be added | Mass (the weight of a compound) | |||
|---|---|---|---|---|
| Mother liquor concentration | 1mg | 5mg | 10mg | 20mg |
| 1mM | 2.5814 mL | 12.9069 mL | 25.8138 mL | 51.6276 mL |
| 5mM | 0.5163 mL | 2.5814 mL | 5.1628 mL | 10.3255 mL |
| 10mM | 0.2581 mL | 1.2907 mL | 2.5814 mL | 5.1628 mL |
| 20mM | 0.1291 mL | 0.6453 mL | 1.2907 mL | 2.5814 mL |
This equation is commonly abbreviated as: C1 V1 = C2 V2
- (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
- (2) Be sure to add the solvent(s) in order.