Home > Signaling Pathways>Anti-infection>Bacterial>Tetracycline (NSC108579)
Tetracycline (NSC108579)

This product is for research use only, not for human use. We do not sell to patients.

Tetracycline (NSC108579)
For small sizes, please check our retail website as below: www.invivochem.com
Size Price Stock
50g$445Check With Us
100g$645Check With Us
200g$965Check With Us

Cat #: V16132 CAS #: 60-54-8 Purity ≥ 98%

Description: Tetracycline (NSC-108579, Sumycin among others) is a potent and broad-spectrum antibiotic used to treat a number of infections such as gram-positive and gram-negative bacteria.

References: Chopra I, et al. Tetracycline antibiotics: mode of action, applications, molecular biology, and epidemiology ofbacterial resistance. Microbiol Mol Biol Rev. 2001 Jun;65(2):232-60.

Top Publications Citing Invivochem Products
Publications Citing InvivoChem Products

Product Promise

Promise
Molecular Weight (MW)444.43
Molecular FormulaC22H24N2O8
CAS No.60-54-8
SMILES CodeO=C(C(C1=O)=C(O)[C@@H](N(C)C)[C@]2([H])C[C@]3([H])[C@](C)(O)C4=C(C(C3=C(O)[C@@]21O)=O)C(O)=CC=C4)N   
SynonymsNSC 108579; NSC-108579; NSC108579; Mericycline; Micycline; Neocycline
ProtocolIn VitroTetracycline shows susceptibilfty of V. vulnlflcus strain B3547 with MIC value of 0.5g/mL.
In VivoTetracycline (3 mg/kg; i.p. every 12 h until survive) survives mice from bacteremia.
These protocols are for reference only. InvivoChem does not independently validate these methods.
Preparing Stock Solutions
Solvent volume to be added Mass (the weight of a compound)
Mother liquor concentration 1mg5mg10mg20mg
1mM2.2501 mL11.2504 mL22.5007 mL45.0015 mL
5mM0.4500 mL2.2501 mL4.5001 mL9.0003 mL
10mM0.2250 mL1.1250 mL2.2501 mL4.5001 mL
20mM0.1125 mL0.5625 mL1.1250 mL2.2501 mL
Quality Control Documentation
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start) × Volume(start) = Concentration(final) × Volume(final)

This equation is commonly abbreviated as: C1 V1 = C2 V2

Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals
Step Two: Enter the in vivo formulation
%DMSO + % + %Tween 80 + %ddH2O

Calculation Results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH2O,mix and clarify.
Note:
  • (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
  • (2) Be sure to add the solvent(s) in order.