T-1105
This product is for research use only, not for human use. We do not sell to patients.
For small sizes, please check our retail website as below: www.invivochem.com
| Size | Price | Stock |
|---|---|---|
| 2g | $400 | Check With Us |
| 5g | $650 | Check With Us |
| 10g | $975 | Check With Us |
: Cat #: V7654 CAS #: 55321-99-8 Purity ≥ 99%
Description: T-1105 (T1105), an analog of T-705 (favipiravir), is a novel and potent broad-spectrum antiviral inhibitor that inhibits the polymerases of RNA viruses after being converted to the actiive form: ribonucleoside triphosphate (RTP) metabolite.
Top Publications Citing Invivochem Products
Publications Citing InvivoChem Products
Product Promise
- Physicochemical and Storage Information
- Protocol
- Related Biological Data
- Stock Solution Preparation
- Quality Control Documentation
| Molecular Weight (MW) | 139.11 |
|---|---|
| Molecular Formula | C5H5N3O2 |
| CAS No. | 55321-99-8 |
| SMILES Code | O=C1C(C(N)=O)=NC=CN1 |
| Synonyms | T-1105; T 1105; T1105 |
| Protocol | In Vitro | T-1105 has antiviral activity against various RNA viruses, including Zika virus (ZIKV), influenza virus, arenaviruses, bunyaviruses, West Nile virus (WNV), yellow fever virus (YFV), and foot-and-mouth disease virus (FMDV). |
|---|---|---|
| In Vivo | T-1105 (Oral, 200 mg/kg, twice daily for 6 days) effectively inhibits the virus replication in the infected pigs. |
These protocols are for reference only. InvivoChem does not
independently validate these methods.
| Solvent volume to be added | Mass (the weight of a compound) | |||
|---|---|---|---|---|
| Mother liquor concentration | 1mg | 5mg | 10mg | 20mg |
| 1mM | 7.1886 mL | 35.9428 mL | 71.8856 mL | 143.7711 mL |
| 5mM | 1.4377 mL | 7.1886 mL | 14.3771 mL | 28.7542 mL |
| 10mM | 0.7189 mL | 3.5943 mL | 7.1886 mL | 14.3771 mL |
| 20mM | 0.3594 mL | 1.7971 mL | 3.5943 mL | 7.1886 mL |
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start)
×
Volume(start)
=
Concentration(final)
×
Volume(final)
This equation is commonly abbreviated as: C1 V1 = C2 V2
Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg
Average weight of animals g
Dosing volume per animal µL
Number of animals
Step Two: Enter the in vivo formulation
%DMSO
+
%
+
%Tween 80
+
%ddH2O
Calculation Results:
Working concentration:
mg/ml;
Method for preparing DMSO master liquid:
mg
drug pre-dissolved in
µL
DMSO(Master liquid concentration
mg/mL)
,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation:
Take
µL
DMSO master liquid, next add
µL
PEG300, mix and clarify, next add
µL
Tween 80,mix and clarify, next add
µL
ddH2O,mix and clarify.
Note:
- (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
- (2) Be sure to add the solvent(s) in order.