CBR-5884
This product is for research use only, not for human use. We do not sell to patients.
For small sizes, please check our retail website as below: www.invivochem.com
| Size | Price | Stock |
|---|---|---|
| 250mg | $915 | To Be Confirmed |
| 500mg | $1260 | To Be Confirmed |
| 1g | $1890 | To Be Confirmed |
: Cat #: V5026 CAS #: 681159-27-3 Purity ≥ 98%
Description: CBR-5884 is a novel, potent, and selective inhibitor of phosphoglycerate dehydrogenase (PHGDH) with an IC50 of 33 μM and with anticancer activities.
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- Physicochemical and Storage Information
- Protocol
- Related Biological Data
- Stock Solution Preparation
- Quality Control Documentation
| Molecular Weight (MW) | 336.39 |
|---|---|
| Molecular Formula | C14H12N2O4S2 |
| CAS No. | 681159-27-3 |
| Storage | -20℃ for 3 years in powder formr |
| -80℃ for 2 years in solvent | |
| SMILES Code | O=C(C1=CC=CO1)NC2=C(SC#N)C(C)=C(C(OCC)=O)S2 |
| Synonyms | CBR-5884; CBR 5884; CBR5884 |
| Protocol | In Vitro | CBR-5884 (15 or 30 μM; 3-5 days) selectively inhibits the proliferation of melanoma and breast cancer lines that have a high propensity for serine synthesis. |
|---|
These protocols are for reference only. InvivoChem does not
independently validate these methods.
| Solvent volume to be added | Mass (the weight of a compound) | |||
|---|---|---|---|---|
| Mother liquor concentration | 1mg | 5mg | 10mg | 20mg |
| 1mM | 2.9727 mL | 14.8637 mL | 29.7274 mL | 59.4548 mL |
| 5mM | 0.5945 mL | 2.9727 mL | 5.9455 mL | 11.8910 mL |
| 10mM | 0.2973 mL | 1.4864 mL | 2.9727 mL | 5.9455 mL |
| 20mM | 0.1486 mL | 0.7432 mL | 1.4864 mL | 2.9727 mL |
The molarity calculator equation
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The dilution calculator equation
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This equation is commonly abbreviated as: C1 V1 = C2 V2
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Step One: Enter information below
Dosage mg/kg
Average weight of animals g
Dosing volume per animal µL
Number of animals
Step Two: Enter the in vivo formulation
%DMSO
+
%
+
%Tween 80
+
%ddH2O
Calculation Results:
Working concentration:
mg/ml;
Method for preparing DMSO master liquid:
mg
drug pre-dissolved in
µL
DMSO(Master liquid concentration
mg/mL)
,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation:
Take
µL
DMSO master liquid, next add
µL
PEG300, mix and clarify, next add
µL
Tween 80,mix and clarify, next add
µL
ddH2O,mix and clarify.
Note:
- (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
- (2) Be sure to add the solvent(s) in order.