UK-383367

This product is for research use only, not for human use. We do not sell to patients.

UK-383367
For small sizes, please check our retail website as below: www.invivochem.com
Size Price
100mg$800
200mg$1200
500mg$2025
1μgGet quote

Cat #: V27826 CAS #: 348622-88-8 Purity ≥ 99%

Description: UK-383367 (UK383367; UK 383367) is a novel and potent nonpeptide inhibitor of BMP-1 (bone morphogenetic protein 1, also called procollagen C-proteinase; PCP) with dermal anti-scarring activity.

References: Allan GA, Gedge JI, Nedderman AN, Roffey SJ, Small HF, Webster R.Pharmacokinetics and metabolism of UK-383,367 in rats and dogs: a rationale for long-lived plasma radioactivity.Xenobiotica. 2006 May;36(5):399-418.

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Product Promise

Promise
Molecular Weight (MW)324.38
Molecular FormulaC15H24N4O4
CAS No.348622-88-8
SMILES CodeO=C(NO)C[C@@H](CCCC1CCCCC1)C2=NC(C(N)=O)=NO2
SynonymsUK-383367, UK 383367, UK383367
Preparing Stock Solutions
Solvent volume to be added Mass (the weight of a compound)
Mother liquor concentration 1mg5mg10mg20mg
1mM3.0828 mL15.4140 mL30.8280 mL61.6561 mL
5mM0.6166 mL3.0828 mL6.1656 mL12.3312 mL
10mM0.3083 mL1.5414 mL3.0828 mL6.1656 mL
20mM0.1541 mL0.7707 mL1.5414 mL3.0828 mL
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start) × Volume(start) = Concentration(final) × Volume(final)

This equation is commonly abbreviated as: C1 V1 = C2 V2

Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals
Step Two: Enter the in vivo formulation
%DMSO + % + %Tween 80 + %ddH2O

Calculation Results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH2O,mix and clarify.
Note:
  • (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
  • (2) Be sure to add the solvent(s) in order.