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Duvoglustat (1-Deoxynojirimycin)

This product is for research use only, not for human use. We do not sell to patients.

Duvoglustat (1-Deoxynojirimycin)
For small sizes, please check our retail website as below: www.invivochem.com
Size Price Stock
250mg$800To Be Confirmed
500mg$1350To Be Confirmed
1g$2025To Be Confirmed

Cat #: V32050 CAS #: 19130-96-2 Purity ≥ 99%

Description: Duvoglustat (Moranoline; deoxynojirimycin; 1-Deoxynojirimycin; AT-2220; DNJ) is a novel and potent alpha-glucosidase inhibitor found in mulberry leaves and has antihyperglycemic, anti-obesity, and antiviral activities.

References: Gao K, et al. 1-Deoxynojirimycin: Occurrence, Extraction, Chemistry, Oral Pharmacokinetics, Biological Activities and In Silico Target Fishing. Molecules. 2016 Nov 23;21(11). pii: E1600.

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Molecular Weight (MW)163.17
Molecular FormulaC6H13NO4
CAS No.19130-96-2
SMILES Code O[C@@H]1[C@@H](CO)NC[C@H](O)[C@H]1O
SynonymsBAY-h-5595; BAY-h 5595; 1-deoxynojirimycin; Duvoglustat Free Base; BAY-h5595;
Preparing Stock Solutions
Solvent volume to be added Mass (the weight of a compound)
Mother liquor concentration 1mg5mg10mg20mg
1mM6.1286 mL30.6429 mL61.2858 mL122.5716 mL
5mM1.2257 mL6.1286 mL12.2572 mL24.5143 mL
10mM0.6129 mL3.0643 mL6.1286 mL12.2572 mL
20mM0.3064 mL1.5321 mL3.0643 mL6.1286 mL
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start) × Volume(start) = Concentration(final) × Volume(final)

This equation is commonly abbreviated as: C1 V1 = C2 V2

Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals
Step Two: Enter the in vivo formulation
%DMSO + % + %Tween 80 + %ddH2O

Calculation Results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH2O,mix and clarify.
Note:
  • (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
  • (2) Be sure to add the solvent(s) in order.