CID-4694321

This product is for research use only, not for human use. We do not sell to patients.

CID-4694321
For small sizes, please check our retail website as below: www.invivochem.com
Size Price Stock
250mg$1250Check With Us
500mg$1950Check With Us
1g$2925Check With Us

Cat #: V2298 CAS #: 1462267-08-8 Purity ≥ 99%

Description: CID-4694321 (also known as ML-266; ML266; CID-4694321) is a novel and potent activator of GCase (glucocerebrosidase) with the potential to be used for treating Gaucher disease.

References: Rogers S, et al. Discovery, SAR, and Biological Evaluation of Non-inhibitory Chaperones of Glucocerebrosidase. 2012 Mar 27 [updated 2013 Mar 7].

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Product Promise

Promise
Molecular Weight (MW)496.35
Molecular FormulaC24H22BrN3O4
CAS No.1462267-08-8
SMILES CodeCN(C1=CC=CC=C1)C(CNC(C2=CC=CC=C2OCC(NC3=CC=C(C=C3)Br)=O)=O)=O
SynonymsCID-46943215; CID 46943215; CID46943215; ML266; ML 266; ML-266
Preparing Stock Solutions
Solvent volume to be added Mass (the weight of a compound)
Mother liquor concentration 1mg5mg10mg20mg
1mM2.0147 mL10.0735 mL20.1471 mL40.2941 mL
5mM0.4029 mL2.0147 mL4.0294 mL8.0588 mL
10mM0.2015 mL1.0074 mL2.0147 mL4.0294 mL
20mM0.1007 mL0.5037 mL1.0074 mL2.0147 mL
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
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Volume
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Molecular Weight*
The dilution calculator equation
Concentration(start) × Volume(start) = Concentration(final) × Volume(final)

This equation is commonly abbreviated as: C1 V1 = C2 V2

Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals
Step Two: Enter the in vivo formulation
%DMSO + % + %Tween 80 + %ddH2O

Calculation Results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH2O,mix and clarify.
Note:
  • (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
  • (2) Be sure to add the solvent(s) in order.