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Aramchol (C20-FABAC)

This product is for research use only, not for human use. We do not sell to patients.

Aramchol (C20-FABAC)
For small sizes, please check our retail website as below: www.invivochem.com
Size Price Stock
100mg$750Check With Us
200mg$1125Check With Us
500mg$1900Check With Us
email: [email protected]        [email protected]

Cat #: V8148 CAS #: 246529-22-6 Purity ≥ 98%

Description: Aramchol (Arachidyl amido cholanoic acid; C20-FABAC), a conjugate of cholic acid and arachidic acid, is a cholesterol solubilizer that prevents gallstone formation in inbred mice.

References: Safadi R, et al. The fatty acid-bile acid conjugate Aramchol reduces liver fat content in patients with nonalcoholic fatty liver disease. Clin Gastroenterol Hepatol. 2014 Dec;12(12):2085-91.e1.

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Molecular Weight (MW)702.10
Molecular FormulaC44H79NO5
CAS No.246529-22-6
SMILES CodeCCCCCCCCCCCCCCCCCCCC(=O)N[C@H]1CC[C@]2([C@@H](C1)C[C@H]([C@@H]3[C@@H]2C[C@@H]([C@]4([C@H]3CC[C@@H]4[C@H](C)CCC(=O)O)C)O)O)C 
SynonymsAramchol; Arachidyl amido cholanoic acid; Icomidocholic acid
Preparing Stock Solutions
Solvent volume to be added Mass (the weight of a compound)
Mother liquor concentration 1mg5mg10mg20mg
1mM1.4243 mL7.1215 mL14.2430 mL28.4860 mL
5mM0.2849 mL1.4243 mL2.8486 mL5.6972 mL
10mM0.1424 mL0.7121 mL1.4243 mL2.8486 mL
20mM0.0712 mL0.3561 mL0.7121 mL1.4243 mL
Quality Control Documentation
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
 
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Concentration
 
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Volume
 
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Molecular Weight*
The dilution calculator equation
Concentration(start) × Volume(start) = Concentration(final) × Volume(final)

This equation is commonly abbreviated as: C1 V1 = C2 V2

Concentration(start)
C1
 
×
 
Volume(start)
V1
 
=
 
Concentration(final)
C2
 
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Volume(final)
V2
Step One: Enter information below
Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals
Step Two: Enter the in vivo formulation
%DMSO + % + %Tween 80 + %ddH2O
Calculation Results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH2O,mix and clarify.
Note:
  • (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
  • (2) Be sure to add the solvent(s) in order.