SCD1 inhibitor-3
This product is for research use only, not for human use. We do not sell to patients.
For small sizes, please check our retail website as below: www.invivochem.com
| Size | Price | Stock |
|---|---|---|
| 100mg | $2500 | Check With Us |
| 200mg | $3750 | Check With Us |
| 500mg | $6325 | Check With Us |
: Cat #: V4456 CAS #: 1282606-48-7 Purity ≥ 99%
Description: SCD1 inhibitor-3 is a potent SCD1 inhibitor.
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| Molecular Weight (MW) | 393.37 |
|---|---|
| Molecular Formula | C19H16FN7O2 |
| CAS No. | 1282606-48-7 |
| SMILES Code | O=C(C1=NNC(N2C=NN(CC3=CC=C(F)C=C3)C2=O)=C1)NCC4=CC=CN=C4 |
| Synonyms | SCD1 inhibitor-3; FUN06487; FUN-06487; FUN 06487; |
| Protocol | In Vivo | SCD1 inhibitor-3 (2~10 mg/kg; p.o.; 4 hours) makes a dose-responsive reduction of plasma triglycerides desaturation index. SCD1 inhibitor-3 (compound 17a) (5 mg/kg; p.o.; 4 hours) reduces the plasma C16:1/C16:0 triglycerides desaturation index by 54 %. |
|---|
These protocols are for reference only. InvivoChem does not
independently validate these methods.
| Solvent volume to be added | Mass (the weight of a compound) | |||
|---|---|---|---|---|
| Mother liquor concentration | 1mg | 5mg | 10mg | 20mg |
| 1mM | 2.5421 mL | 12.7107 mL | 25.4214 mL | 50.8427 mL |
| 5mM | 0.5084 mL | 2.5421 mL | 5.0843 mL | 10.1685 mL |
| 10mM | 0.2542 mL | 1.2711 mL | 2.5421 mL | 5.0843 mL |
| 20mM | 0.1271 mL | 0.6355 mL | 1.2711 mL | 2.5421 mL |
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start)
×
Volume(start)
=
Concentration(final)
×
Volume(final)
This equation is commonly abbreviated as: C1 V1 = C2 V2
Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg
Average weight of animals g
Dosing volume per animal µL
Number of animals
Step Two: Enter the in vivo formulation
%DMSO
+
%
+
%Tween 80
+
%ddH2O
Calculation Results:
Working concentration:
mg/ml;
Method for preparing DMSO master liquid:
mg
drug pre-dissolved in
µL
DMSO(Master liquid concentration
mg/mL)
,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation:
Take
µL
DMSO master liquid, next add
µL
PEG300, mix and clarify, next add
µL
Tween 80,mix and clarify, next add
µL
ddH2O,mix and clarify.
Note:
- (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
- (2) Be sure to add the solvent(s) in order.