TPPU

This product is for research use only, not for human use. We do not sell to patients.

TPPU
For small sizes, please check our retail website as below: www.invivochem.com
Size Price Stock
100mg$750Check With Us
250mg$1250Check With Us
500mg$1875Check With Us

Cat #: V33532 CAS #: 1222780-33-7 Purity ≥ 99%

Description: TTPU is a soluble epoxide hydrolase (sEH) inhibitor with IC50 of 37 and 3.7 nM for monkey and human sEH, respectively.

References: Ulu A, et al. Pharmacokinetics and in vivo potency of soluble epoxide hydrolase inhibitors in cynomolgus monkeys. Br J Pharmacol. 2012 Mar;165(5):1401-12.

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Molecular Weight (MW)359.34
Molecular FormulaC16H20F3N3O3
CAS No.1222780-33-7
SMILES CodeCCC(N(CC1)CCC1NC(NC2=CC=C(OC(F)(F)F)C=C2)=O)
SynonymsTPPU
Preparing Stock Solutions
Solvent volume to be added Mass (the weight of a compound)
Mother liquor concentration 1mg5mg10mg20mg
1mM2.7829 mL13.9144 mL27.8288 mL55.6576 mL
5mM0.5566 mL2.7829 mL5.5658 mL11.1315 mL
10mM0.2783 mL1.3914 mL2.7829 mL5.5658 mL
20mM0.1391 mL0.6957 mL1.3914 mL2.7829 mL
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start) × Volume(start) = Concentration(final) × Volume(final)

This equation is commonly abbreviated as: C1 V1 = C2 V2

Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals
Step Two: Enter the in vivo formulation
%DMSO + % + %Tween 80 + %ddH2O

Calculation Results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH2O,mix and clarify.
Note:
  • (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
  • (2) Be sure to add the solvent(s) in order.