Dabigatran ethyl ester

This product is for research use only, not for human use. We do not sell to patients.

Dabigatran ethyl ester
For small sizes, please check our retail website as below: www.invivochem.com
Size Price Stock
250mg$1160To Be Confirmed
500mg$1650To Be Confirmed
1g$2475To Be Confirmed

Cat #: V4932 CAS #: 429658-95-7 Purity ≥ 98%

Description: Dabigatran ethyl ester is the ethyl ester form of dabigatran which is an antithrombotic drug used to treat blood clot.

References: Simon Michaelis, Anett Marais, Anna K. Schrey, et al. Dabigatran and Dabigatran Ethyl Ester: Potent Inhibitors of Ribosyldihydronicotinamide Dehydrogenase (NQO2). J. Med. Chem., 2012, 55 (8):3934-3944

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Product Promise

Promise
Molecular Weight (MW)499.56
Molecular FormulaC₂₇H₂₉N₇O₃
CAS No.429658-95-7
Storage-20℃ for 3 years in powder formr
-80℃ for 2 years in solvent
SMILES CodeO=C(OCC)CCN(C(C1=CC=C2C(N=C(CNC3=CC=C(C(N)=N)C=C3)N2C)=C1)=O)C4=NC=CC=C4
SynonymsBIBR-951CL; BIBR 951CL; BIBR951CL; UNII-KJ4EH9410G; Dabigatran ethyl ester;
Preparing Stock Solutions
Solvent volume to be added Mass (the weight of a compound)
Mother liquor concentration 1mg5mg10mg20mg
1mM2.0018 mL10.0088 mL20.0176 mL40.0352 mL
5mM0.4004 mL2.0018 mL4.0035 mL8.0070 mL
10mM0.2002 mL1.0009 mL2.0018 mL4.0035 mL
20mM0.1001 mL0.5004 mL1.0009 mL2.0018 mL
Quality Control Documentation
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start) × Volume(start) = Concentration(final) × Volume(final)

This equation is commonly abbreviated as: C1 V1 = C2 V2

Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals
Step Two: Enter the in vivo formulation
%DMSO + % + %Tween 80 + %ddH2O

Calculation Results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH2O,mix and clarify.
Note:
  • (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
  • (2) Be sure to add the solvent(s) in order.