WYC-209

This product is for research use only, not for human use. We do not sell to patients.

WYC-209
For small sizes, please check our retail website as below: www.invivochem.com
Size Price Stock
100mg$2650Check With Us
200mg$3975Check With Us
500mg$6710Check With Us

Cat #: V31665 CAS #: 2131803-90-0 Purity ≥ 99%

Description: WYC-209, a synthetic retinoid, is a retinoic acid receptor (RAR) agonist.

References: Chen J, et al. Inhibition of cancer stem cell like cells by a synthetic retinoid. Nat Commun. 2018 Apr 11;9(1):1406.

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Molecular Weight (MW)368.45
Molecular FormulaC20H20N2O3S
CAS No.2131803-90-0
SMILES CodeO=C(OCC)C1=CC=C(C#CC2=CC(C(C)(C)CCS3=O)=C3C=C2)C=C1
SynonymsWYC-209; WYC 209; WYC209
ProtocolIn VitroWYC-209 (10 μM; 24 hours) is able to inhibit and block growth of TRCs of human tumor cells in culture with a long-lasting effect.
In VivoWYC-209 (0.022-0.22 mg/kg; i.v.; once every two days for 25 days) inhibits tumor metastasis in C57BL/6 mice bearing lung metastases.
These protocols are for reference only. InvivoChem does not independently validate these methods.
Preparing Stock Solutions
Solvent volume to be added Mass (the weight of a compound)
Mother liquor concentration 1mg5mg10mg20mg
1mM2.7141 mL13.5704 mL27.1407 mL54.2814 mL
5mM0.5428 mL2.7141 mL5.4281 mL10.8563 mL
10mM0.2714 mL1.3570 mL2.7141 mL5.4281 mL
20mM0.1357 mL0.6785 mL1.3570 mL2.7141 mL
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
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Concentration
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Volume
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Molecular Weight*
The dilution calculator equation
Concentration(start) × Volume(start) = Concentration(final) × Volume(final)

This equation is commonly abbreviated as: C1 V1 = C2 V2

Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals
Step Two: Enter the in vivo formulation
%DMSO + % + %Tween 80 + %ddH2O

Calculation Results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH2O,mix and clarify.
Note:
  • (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
  • (2) Be sure to add the solvent(s) in order.