Acitretin (Ro 10-1670)
This product is for research use only, not for human use. We do not sell to patients.
For small sizes, please check our retail website as below: www.invivochem.com
| Size | Price | Stock |
|---|---|---|
| 500mg | $380 | Check With Us |
| 5g | $2050 | Check With Us |
| 10g | $3075 | Check With Us |
: Cat #: V2033 CAS #: 55079-83-9 Purity ≥ 98%
Description: Acitretin (also known as Etretin, RO 10-1670; Soriatane; Etretin; Neotigason) is a novel, potent, orally bioavailable, second generation retinoid used for psoriasis.
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| Molecular Weight (MW) | 326.43 |
|---|---|
| Molecular Formula | C21H26O3 |
| CAS No. | 55079-83-9 |
| Storage | -20℃ for 3 years in powder formr |
| -80℃ for 2 years in solvent | |
| Solubility In Vitro | DMSO: 20 mg/mL (61.3 mM)r |
| Water: <1 mg/mLr | |
| Ethanol: <1 mg/mL | |
| SMILES Code | CC1=CC(=C(C(=C1C=CC(=CC=CC(=CC(=O)O)C)C)C)C)OC |
| Synonyms | Etretin, U 0279; U-0279; U0279; RO 10-1670; Ro 10-1670; Ro-10-1670; Ro10-1670; Ro 10-1670/000; Acitretin; Soriatane; Neotigason |
| Protocol | In Vivo | Acitretin (10 mg/kg; i.p. for 7 days) increases IL-6 in the central nervous system of Alzheimer’s disease model mice. |
|---|
These protocols are for reference only. InvivoChem does not
independently validate these methods.
| Solvent volume to be added | Mass (the weight of a compound) | |||
|---|---|---|---|---|
| Mother liquor concentration | 1mg | 5mg | 10mg | 20mg |
| 1mM | 3.0634 mL | 15.3172 mL | 30.6344 mL | 61.2689 mL |
| 5mM | 0.6127 mL | 3.0634 mL | 6.1269 mL | 12.2538 mL |
| 10mM | 0.3063 mL | 1.5317 mL | 3.0634 mL | 6.1269 mL |
| 20mM | 0.1532 mL | 0.7659 mL | 1.5317 mL | 3.0634 mL |
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start)
×
Volume(start)
=
Concentration(final)
×
Volume(final)
This equation is commonly abbreviated as: C1 V1 = C2 V2
Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg
Average weight of animals g
Dosing volume per animal µL
Number of animals
Step Two: Enter the in vivo formulation
%DMSO
+
%
+
%Tween 80
+
%ddH2O
Calculation Results:
Working concentration:
mg/ml;
Method for preparing DMSO master liquid:
mg
drug pre-dissolved in
µL
DMSO(Master liquid concentration
mg/mL)
,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation:
Take
µL
DMSO master liquid, next add
µL
PEG300, mix and clarify, next add
µL
Tween 80,mix and clarify, next add
µL
ddH2O,mix and clarify.
Note:
- (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
- (2) Be sure to add the solvent(s) in order.