HX 531

This product is for research use only, not for human use. We do not sell to patients.

HX 531
For small sizes, please check our retail website as below: www.invivochem.com
Size Price Stock
100mg$750Check With Us
200mg$1125Check With Us
500mg$1900Check With Us

Cat #: V7843 CAS #: 188844-34-0 Purity ≥ 99%

Description: HX-531 is a novel and potent antagonist of retinoid X receptors (RXR) with an IC50 value of 18 nM.

References: Konta T, et al. Selective roles of retinoic acid receptor and retinoid x receptor in the suppression of apoptosis by all-trans-retinoic acid. J Biol Chem. 2001 Apr 20;276(16):12697-701. 

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Promise
Molecular Weight (MW)483.56
Molecular FormulaC29H29N3O4
CAS No.188844-34-0
SMILES CodeO=C(O)C1=CC=C(C2=NC3=CC([N+]([O-])=O)=CC=C3N(C)C4=CC5=C(C(C)(C)CCC5(C)C)C=C42)C=C1 
SynonymsHX 531; HX-531; HX531
Preparing Stock Solutions
Solvent volume to be added Mass (the weight of a compound)
Mother liquor concentration 1mg5mg10mg20mg
1mM2.0680 mL10.3400 mL20.6800 mL41.3599 mL
5mM0.4136 mL2.0680 mL4.1360 mL8.2720 mL
10mM0.2068 mL1.0340 mL2.0680 mL4.1360 mL
20mM0.1034 mL0.5170 mL1.0340 mL2.0680 mL
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start) × Volume(start) = Concentration(final) × Volume(final)

This equation is commonly abbreviated as: C1 V1 = C2 V2

Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals
Step Two: Enter the in vivo formulation
%DMSO + % + %Tween 80 + %ddH2O

Calculation Results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH2O,mix and clarify.
Note:
  • (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
  • (2) Be sure to add the solvent(s) in order.