NVP-VID-400

This product is for research use only, not for human use. We do not sell to patients.

NVP-VID-400
For small sizes, please check our retail website as below: www.invivochem.com
Size Price Stock
250mg$1400Check With Us
500mg$2000Check With Us
1g$3000Check With Us

Cat #: V26795 CAS #: 174262-13-6 Purity ≥ 99%

Description: NVP-VID-400, formerly known as SDZ285-428, is CYP24A1 inhibitor.

References: Lepesheva GI, et al. CYP51: A major drug target in the cytochrome P450 superfamily. Lipids. 2008 Dec;43(12):1117-25.

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Molecular Weight (MW)401.89
Molecular FormulaC24H20ClN3O
CAS No.174262-13-6
SMILES CodeO=C(C1=CC=C(C2=CC=C(Cl)C=C2)C=C1)NCC(N3C=CN=C3)C4=CC=CC=C4
SynonymsSDZ285428; SDZ 285428; SDZ-285428; SDZ285-428; SDZ 285-428; SDZ-285-428; NVP-VID-400; NVP-VID 400; NVP-VID400;
ProtocolIn VivoSpecific inhibition of protozoan CYP51 can potentially provide treatment for human trypanosomiases.
These protocols are for reference only. InvivoChem does not independently validate these methods.
Preparing Stock Solutions
Solvent volume to be added Mass (the weight of a compound)
Mother liquor concentration 1mg5mg10mg20mg
1mM2.4882 mL12.4412 mL24.8824 mL49.7649 mL
5mM0.4976 mL2.4882 mL4.9765 mL9.9530 mL
10mM0.2488 mL1.2441 mL2.4882 mL4.9765 mL
20mM0.1244 mL0.6221 mL1.2441 mL2.4882 mL
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
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Concentration
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Volume
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Molecular Weight*
The dilution calculator equation
Concentration(start) × Volume(start) = Concentration(final) × Volume(final)

This equation is commonly abbreviated as: C1 V1 = C2 V2

Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals
Step Two: Enter the in vivo formulation
%DMSO + % + %Tween 80 + %ddH2O

Calculation Results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH2O,mix and clarify.
Note:
  • (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
  • (2) Be sure to add the solvent(s) in order.