ent-Atorvastatin
This product is for research use only, not for human use. We do not sell to patients.
For small sizes, please check our retail website as below: www.invivochem.com
| Size | Price | Stock |
|---|---|---|
| 100mg | $1250 | Check With Us |
| 200mg | $1875 | Check With Us |
| 500mg | $3165 | Check With Us |
: Cat #: V20588 CAS #: 501121-34-2 Purity ≥ 99%
Description: ent-Atorvastatin [(3S,5S)-Atorvastatin] is an inactive isomer/enantiomer of Atorvastatin, which is a HMGCR (HMG-CoA reductase) inhibitor and an approved blockbuster drug of the statin class of LDL cholesterol-lowering/hypolipidemic drug.
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| Molecular Weight (MW) | 558.64 |
|---|---|
| Molecular Formula | C33H35FN2O5 |
| CAS No. | 501121-34-2 |
| SMILES Code | CC(C)c1c(c(c(n1CC[C@@H](C[C@@H](CC(=O)O)O)O)c2ccc(cc2)F)c3ccccc3)C(=O)Nc4ccccc4 |
| Synonyms | 3S,5S-Atorvastatin, Atorvastatin calcium trihydrate impurity E, ent-Atorvastatin |
| Protocol | In Vitro | Atorvastatin and its inactive enantiomer (3S,5S)-Atorvastatin increases CYP2B and CYP3A mRNA content with equal ability. |
|---|
These protocols are for reference only. InvivoChem does not
independently validate these methods.
| Solvent volume to be added | Mass (the weight of a compound) | |||
|---|---|---|---|---|
| Mother liquor concentration | 1mg | 5mg | 10mg | 20mg |
| 1mM | 1.7901 mL | 8.9503 mL | 17.9006 mL | 35.8012 mL |
| 5mM | 0.3580 mL | 1.7901 mL | 3.5801 mL | 7.1602 mL |
| 10mM | 0.1790 mL | 0.8950 mL | 1.7901 mL | 3.5801 mL |
| 20mM | 0.0895 mL | 0.4475 mL | 0.8950 mL | 1.7901 mL |
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start)
×
Volume(start)
=
Concentration(final)
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Volume(final)
This equation is commonly abbreviated as: C1 V1 = C2 V2
Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg
Average weight of animals g
Dosing volume per animal µL
Number of animals
Step Two: Enter the in vivo formulation
%DMSO
+
%
+
%Tween 80
+
%ddH2O
Calculation Results:
Working concentration:
mg/ml;
Method for preparing DMSO master liquid:
mg
drug pre-dissolved in
µL
DMSO(Master liquid concentration
mg/mL)
,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation:
Take
µL
DMSO master liquid, next add
µL
PEG300, mix and clarify, next add
µL
Tween 80,mix and clarify, next add
µL
ddH2O,mix and clarify.
Note:
- (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
- (2) Be sure to add the solvent(s) in order.