IBMX

This product is for research use only, not for human use. We do not sell to patients.

IBMX
For small sizes, please check our retail website as below: www.invivochem.com
Size Price Stock
500mg$250Check With Us
1g$450Check With Us
5g$1140Check With Us

Cat #: V4097 CAS #: 28822-58-4 Purity ≥ 98%

Description: IBMX is a nonspecific, broad-spectrum, competitive inhibitor of phosphodiesterase (PDE) inhibitor, with IC50s of 6.5, 26.3 and 31.7 μM for PDE3, PDE4 and PDE5, respectively.

References: Tio M, et al. Roles of db-cAMP, IBMX and RA in aspects of neural differentiation of cord blood derived mesenchymal-like stem cells. PLoS One. 2010 Feb 24;5(2):e9398.

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Product Promise

Promise
Molecular Weight (MW)222.25
Molecular FormulaC10H14N4O2
CAS No.28822-58-4
Storage-20℃ for 3 years in powder formr
-80℃ for 2 years in solvent
Solubility In VitroDMSO: ≥ 40 mg/mLr
Water: < 1mg/mLr
Ethanol: N/A
SMILES CodeO=C(N1C)N(CC(C)C)C2=C(NC=N2)C1=O
SynonymsIBMX; 3-Isobutyl-1-methylxanthine; Isobutylmethylxanthine
ProtocolIn VitroIBMX (0.5 mM) induces neural-like cells for neural differentiation of cord blood derived mesenchymal-like stem cells.
These protocols are for reference only. InvivoChem does not independently validate these methods.
Preparing Stock Solutions
Solvent volume to be added Mass (the weight of a compound)
Mother liquor concentration 1mg5mg10mg20mg
1mM4.4994 mL22.4972 mL44.9944 mL89.9888 mL
5mM0.8999 mL4.4994 mL8.9989 mL17.9978 mL
10mM0.4499 mL2.2497 mL4.4994 mL8.9989 mL
20mM0.2250 mL1.1249 mL2.2497 mL4.4994 mL
Quality Control Documentation
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start) × Volume(start) = Concentration(final) × Volume(final)

This equation is commonly abbreviated as: C1 V1 = C2 V2

Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals
Step Two: Enter the in vivo formulation
%DMSO + % + %Tween 80 + %ddH2O

Calculation Results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH2O,mix and clarify.
Note:
  • (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
  • (2) Be sure to add the solvent(s) in order.