EHNA hydrochloride
This product is for research use only, not for human use. We do not sell to patients.
For small sizes, please check our retail website as below: www.invivochem.com
| Size | Price | Stock |
|---|---|---|
| 250mg | $1150 | To Be Confirmed |
| 500mg | $1850 | To Be Confirmed |
| 1g | $2775 | To Be Confirmed |
: Cat #: V30046 CAS #: 58337-38-5 Purity ≥ 99%
Description: EHNA HCl, the hydrochloride salt of EHNA, is a novel and potent inhibitor of adenosine deaminase, also an inhibitor of cGMP-stimulated phosphodiesterase (PDE2) with IC50 of 0.8 - 4 μM.
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- Physicochemical and Storage Information
- Protocol
- Related Biological Data
- Stock Solution Preparation
- Quality Control Documentation
| Molecular Weight (MW) | 313.83 |
|---|---|
| Molecular Formula | C14H24ClN5O |
| CAS No. | 58337-38-5 |
| Synonyms | EHNA hydrochloride |
| Protocol | In Vitro | EHNA completely ablates the ability of cyclic GMP to activate PDE2 activity, whilst having a much smaller inhibitory effect on the unstimulated PDE2 activity. |
|---|
These protocols are for reference only. InvivoChem does not
independently validate these methods.
| Solvent volume to be added | Mass (the weight of a compound) | |||
|---|---|---|---|---|
| Mother liquor concentration | 1mg | 5mg | 10mg | 20mg |
| 1mM | 3.1864 mL | 15.9322 mL | 31.8644 mL | 63.7288 mL |
| 5mM | 0.6373 mL | 3.1864 mL | 6.3729 mL | 12.7458 mL |
| 10mM | 0.3186 mL | 1.5932 mL | 3.1864 mL | 6.3729 mL |
| 20mM | 0.1593 mL | 0.7966 mL | 1.5932 mL | 3.1864 mL |
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
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Volume
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Molecular Weight*
The dilution calculator equation
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Volume(start)
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Volume(final)
This equation is commonly abbreviated as: C1 V1 = C2 V2
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Step One: Enter information below
Dosage mg/kg
Average weight of animals g
Dosing volume per animal µL
Number of animals
Step Two: Enter the in vivo formulation
%DMSO
+
%
+
%Tween 80
+
%ddH2O
Calculation Results:
Working concentration:
mg/ml;
Method for preparing DMSO master liquid:
mg
drug pre-dissolved in
µL
DMSO(Master liquid concentration
mg/mL)
,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation:
Take
µL
DMSO master liquid, next add
µL
PEG300, mix and clarify, next add
µL
Tween 80,mix and clarify, next add
µL
ddH2O,mix and clarify.
Note:
- (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
- (2) Be sure to add the solvent(s) in order.