Abanoquil | CAS 118931-00-3

Abanoquil

This product is for research use only, not for human use. We do not sell to patients.

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Cat #: V5373 CAS #: 118931-00-3 Purity ≥ 98%

Description: Abanoquil, formerly known as UK 52046, is a potent alpha-1 adrenoceptor antagonist. Abanoquil is able to relax contracted tissue strips and induce erectile response when injected intracorporally . The erectile response in the monkeys was not dose-related and compared to the effect of papaverine injections, abanoquil induced a lower level of tumescence and rigidity. Hence, abanoquil might be useful as a facilitator of erection in the pharmacological treatment of erectile dysfunction.

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Related Biological Data
Stock Solution Preparation
Quality Control Documentation

Molecular Weight (MW)	395.459
Molecular Formula	C22H25N3O4
CAS No.	118931-00-3
Synonyms	UK 52046; UK-52046; UK52046; Abanoquil

Preparing Stock Solutions

Solvent volume to be added	Mass (the weight of a compound)
Mother liquor concentration	1mg	5mg	10mg	20mg
1mM	2.5287 mL	12.6435 mL	25.2871 mL	50.5741 mL
5mM	0.5057 mL	2.5287 mL	5.0574 mL	10.1148 mL
10mM	0.2529 mL	1.2644 mL	2.5287 mL	5.0574 mL
20mM	0.1264 mL	0.6322 mL	1.2644 mL	2.5287 mL

Quality Control Documentation	Select Batch Purity ≥ 98% COA MSDS NMR HPLC

The molarity calculator equation

Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)

Mass

Concentration

Volume

Molecular Weight*

The dilution calculator equation

Concentration_(start) × Volume_(start) = Concentration_(final) × Volume_(final)

This equation is commonly abbreviated as: C₁ V₁ = C₂ V₂

Concentration_(start)

Volume_(start)

Concentration_(final)

Volume_(final)

Step One: Enter information below

Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals

Step Two: Enter the in vivo formulation

%DMSO + % + %Tween 80 + %ddH₂O

Calculation Results:

Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.

Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH₂O,mix and clarify.

Note:

(1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
(2) Be sure to add the solvent(s) in order.