YC-137 | CAS 810659-53-1

YC-137

This product is for research use only, not for human use. We do not sell to patients.

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Cat #: V5368 CAS #: 810659-53-1 Purity ≥ 98%

Description: YC-137 (YC137) is a novel and potent BCL-2 inhibitor with anticancer activity. It selectively induces apoptosis of Bcl-2-overexpressing cells and disrupts its interaction with Bid BH3, thereby blocking the anti-apoptotic activity of Bcl-2.

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Related Biological Data
Stock Solution Preparation
Quality Control Documentation

Molecular Weight (MW)	511.57
Molecular Formula	C24H21N3O6S2
CAS No.	810659-53-1
Synonyms	YC-137; YC 137; YC137.

Preparing Stock Solutions

Solvent volume to be added	Mass (the weight of a compound)
Mother liquor concentration	1mg	5mg	10mg	20mg
1mM	1.9548 mL	9.7738 mL	19.5477 mL	39.0953 mL
5mM	0.3910 mL	1.9548 mL	3.9095 mL	7.8191 mL
10mM	0.1955 mL	0.9774 mL	1.9548 mL	3.9095 mL
20mM	0.0977 mL	0.4887 mL	0.9774 mL	1.9548 mL

Quality Control Documentation	Select Batch Purity ≥ 98% COA MSDS NMR HPLC

The molarity calculator equation

Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)

Mass

Concentration

Volume

Molecular Weight*

The dilution calculator equation

Concentration_(start) × Volume_(start) = Concentration_(final) × Volume_(final)

This equation is commonly abbreviated as: C₁ V₁ = C₂ V₂

Concentration_(start)

Volume_(start)

Concentration_(final)

Volume_(final)

Step One: Enter information below

Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals

Step Two: Enter the in vivo formulation

%DMSO + % + %Tween 80 + %ddH₂O

Calculation Results:

Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.

Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH₂O,mix and clarify.

Note:

(1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
(2) Be sure to add the solvent(s) in order.