TH-162 | CAS 38594-96-6

TH-162

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Cat #: V5354 CAS #: 38594-96-6 Purity ≥ 98%

Description: TH-162, formerly known as (R)-PIA and Adenosine, N-(1-methyl-2-phenylethyl)-, (R)- is an A1 adenosine receptor agonist. Affinity for adenosine receptor is approx. 100× that of the (+)-isomer.

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Stock Solution Preparation
Quality Control Documentation

Molecular Weight (MW)	385.42
Molecular Formula	C19H23N5O4
CAS No.	38594-96-6
Synonyms	(R)-PIA; (R)- PIA; (R)-PIA; Adenosine, N-(1-methyl-2-phenylethyl)-, (R)-; L-PIA; L-2-N6-(Phenylisopropyl)adenosine; TH 162; TH-162; TH162

Preparing Stock Solutions

Solvent volume to be added	Mass (the weight of a compound)
Mother liquor concentration	1mg	5mg	10mg	20mg
1mM	2.5946 mL	12.9729 mL	25.9457 mL	51.8914 mL
5mM	0.5189 mL	2.5946 mL	5.1891 mL	10.3783 mL
10mM	0.2595 mL	1.2973 mL	2.5946 mL	5.1891 mL
20mM	0.1297 mL	0.6486 mL	1.2973 mL	2.5946 mL

Quality Control Documentation	Select Batch Purity ≥ 98% COA MSDS NMR HPLC

The molarity calculator equation

Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)

Mass

Concentration

Volume

Molecular Weight*

The dilution calculator equation

Concentration_(start) × Volume_(start) = Concentration_(final) × Volume_(final)

This equation is commonly abbreviated as: C₁ V₁ = C₂ V₂

Concentration_(start)

Volume_(start)

Concentration_(final)

Volume_(final)

Step One: Enter information below

Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals

Step Two: Enter the in vivo formulation

%DMSO + % + %Tween 80 + %ddH₂O

Calculation Results:

Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.

Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH₂O,mix and clarify.

Note:

(1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
(2) Be sure to add the solvent(s) in order.